Policy

A policy is a deliberate system of principles to guide decisions and achieve rational outcomes. A policy is a statement of intent, and is implemented as a procedure or protocol. Policies are generally adopted by the Board of or senior governance body within an organization whereas procedures or protocols would be developed and adopted by senior executive officers. Policies can assist in both subjective and objective decision making. Policies to assist in subjective decision making would usually assist senior management with decisions that must consider the relative merits of a number of factors before making decisions and as a result are often hard to objectively test e.g. work-life balance policy. In contrast policies to assist in objective decision making are usually operational in nature and can be objectively tested e.g. password policy.

The term may apply to government, private sector organizations and groups, as well as individuals. Presidential executive orders, corporate privacy policies, and parliamentary rules of order are all examples of policy. Policy differs from rules or law. While law can compel or prohibit behaviors (e.g. a law requiring the payment of taxes on income), policy merely guides actions toward those that are most likely to achieve a desired outcome.

Policy (Martha Davis album)

Policy is the first solo studio album by Martha Davis, who is better known as the lead singer for the band The Motels. Martha broke up with her band in February 1987, declaring that she was going solo, and by November, she had released her first solo album.

Track listing

Singles

"Don't Tell Me the Time" (Capitol Records #44057) Released: Nov 1987 Charts: Australia #8 / US #80
"Tell It to the Moon" (Capitol Records #44114) Released: Jan 1988 Charts: Australia #65
"Just Like You" (Capitol Records #79188) Released: Mar 1988 Charts: US-FM #15
"Don't Ask Out Loud" (Capitol Records #79188) Released: Mar 1988 Charts: Australia #90
"What Money Might Buy" (Capitol Records AU:#CP 2157) Released: Apr 1988 (Australia only)

Policy (Will Butler album)

Policy is the debut solo album by Will Butler, best known for his work in Canadian indie rock band Arcade Fire. The album was released on March 10, 2015 by Merge Records.

Concept

Butler set out to make an album akin to what he calls "American Music". Butler has stated that "Policy is American music—in the tradition of the Violent Femmes, The Breeders, The Modern Lovers, Bob Dylan, Smokey Robinson, The Magnetic Fields, Ghostface Killah, and John Lennon (I know, but it counts)." He has called this type of music "Music where the holy fool runs afoul of the casual world".

Recording and release

Policy was recorded in a week in Jimi Hendrix's old living room, which is now Studio C at Electric Lady Studios. Butler recorded it during a short break on Arcade Fire's Reflektor tour. All songs were recorded there, with the exception of "Something's Coming", which was recorded in Aaron Dessner's home recording studio, the recording place of The National. Additional work for the song was done in the basement of drummer Jeremy Gara. Most of the instrumentation had been done by Butler, with the exception of drums that were done by Gara, also of Arcade Fire. He also "Had a couple of friends come in to do clarinet, saxophone and backing vocals".

MBP

MBP or mbp may refer to:

Science and technology

Biology

Media

Myelin basic protein

Myelin basic protein (MBP) is a protein believed to be important in the process of myelination of nerves in the nervous system. The myelin sheath is a multi-layered membrane, unique to the nervous system, that functions as an insulator to greatly increase the velocity of axonal impulse conduction. MBP maintains the correct structure of myelin, interacting with the lipids in the myelin membrane.

MBP was initially sequenced in 1971 after isolation from myelin membranes. Since that time, knockout mice deficient in MBP that showed decreased amounts of CNS myelination and a progressive disorder characterized by tremors, seizures, and early death have been developed. The human gene for MBP is on chromosome 18; the protein localizes to the CNS and to various cells of the hematopoietic system.

The pool of MBP in the central nervous system is very diverse, with several splice variants being expressed and a large number of post-translational modifications on the protein, which include phosphorylation, methylation, deamidation, and citrullination. These forms differ by the presence or the absence of short (10 to 20 residues) peptides in various internal locations in the sequence. In general, the major form of MBP is a protein of about 18.5 Kd (170 residues).

Dirucotide

Dirucotide (also known as MBP8298) was developed by two research scientists (Dr. Kenneth G. Warren, MD, FRCP(C) & Ingrid Catz, Senior Scientist) at the University of Alberta for the treatment of Multiple Sclerosis (MS). Dirucotide is a synthetic peptide that consists of 17 amino acids linked in a sequence identical to that of a portion of human myelin basic protein (MBP). The sequence of these 17 amino acids is

Research

Results from a phase II and long-term follow-up trial showed that dirucotide safely delayed median time to disease progression for five years in progressive MS patients with HLA-DR2 or HLA-DR4 immune response genes. It does not seem to be effective in patients with other gene variants.

The drug is exclusively licensed by BioMS Medical Corp., a Canadian-based biotechnology company. BioMS Medical received clearance from the Food & Drug Administration (FDA) to initiate a phase III clinical trial, named MAESTRO-03, for secondary progressive MS patients in January 2007. An additional Phase III clinical trial for dirucotide, MAESTRO-01, is being undertaken in Canada and Europe. In September 2008, the drug was granted FDA fast-track for approval.