Orthopedic cast

An orthopedic cast, body cast, plaster cast, or surgical cast, is a shell, frequently made from plaster or fiberglass, encasing a limb (or, in some cases, large portions of the body) to stabilize and hold anatomical structures, most often a broken bone (or bones), in place until healing is confirmed. It is similar in function to a splint.

Plaster bandages consist of a cotton bandage that has been combined with plaster of paris, which hardens after it has been made wet. Plaster of Paris is calcined gypsum (roasted gypsum), ground to a fine powder by milling. When water is added, the more soluble form of calcium sulfate returns to the relatively insoluble form, and heat is produced.

The setting of unmodified plaster starts about 10 minutes after mixing and is complete in about 45 minutes; however, the cast is not fully dry for 72 hours.

Nowadays bandages of synthetic materials are often used, often knitted fiberglass bandages impregnated with polyurethane, sometimes bandages of thermoplastic. These are lighter and dry much faster than plaster bandages. However, plaster can be more easily moulded to make a snug and therefore more comfortable fit. In addition, plaster is much smoother and does not snag clothing or abrade the skin.

Fossil

Fossils (from Classical Latin fossilis; literally, "obtained by digging") are the preserved remains or traces of animals, plants, and other organisms from the remote past. The totality of fossils, both discovered and undiscovered, and their placement in fossiliferous (fossil-containing) rock formations and sedimentary layers (strata) is known as the fossil record.

The study of fossils across geological time, how they were formed, and the evolutionary relationships between taxa (phylogeny) are some of the most important functions of the science of paleontology. Such a preserved specimen is called a "fossil" if it is older than some minimum age, most often the arbitrary date of 10,000 years. Hence, fossils range in age from the youngest at the start of the Holocene Epoch to the oldest, chemical fossils from the Archaean Eon, up to 3.48 billion years old, or even older, 4.1 billion years old, according to a 2015 study. The observation that certain fossils were associated with certain rock strata led early geologists to recognize a geological timescale in the 19th century. The development of radiometric dating techniques in the early 20th century allowed geologists to determine the numerical or "absolute" age of the various strata and thereby the included fossils.

Calpastatin

Calpastatin is a protein that in humans is encoded by the CAST gene.

The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Several alternatively spliced transcript variants of this gene have been described, but the full-length natures of only some have been determined.

References

External links

Further reading

Winter

Winter is the coldest season of the year in polar and temperate climates, between autumn and spring. Winter is caused by the axis of the Earth in that hemisphere being oriented away from the Sun. Different cultures define different dates as the start of winter, and some use a definition based on weather. When it is winter in the Northern Hemisphere, it is summer in the Southern Hemisphere, and vice versa. In many regions, winter is associated with snow and freezing temperatures. The moment of winter solstice is when the sun's elevation with respect to the North or South Pole is at its most negative value (that is, the sun is at its farthest below the horizon as measured from the pole), meaning this day will have the shortest day and the longest night. The earliest sunset and latest sunrise dates outside the polar regions differ from the date of the winter solstice, however, and these depend on latitude, due to the variation in the solar day throughout the year caused by the Earth's elliptical orbit (see earliest and latest sunrise and sunset).

Winter (Tori Amos song)

"Winter" is a song by American singer-songwriter and musician Tori Amos, first released in 1992. The song was written about Amos' relationship with her father, who is a minister.

Release history

"Winter" was first released as the fourth single from Amos' debut studio album Little Earthquakes. It was released on March 9, 1992 by EastWest Records in the UK and Atlantic Records on November 24 in North America.

The song also appears on Amos' 2003 compilation, Tales of a Librarian. The music video can be seen on the two currently available video collections: Tori Amos: Complete Videos 1991–1998 and Fade to Red.

The single was released globally in a variety of formats with slightly differing artwork and track listings. The most commonly available version is the United States release, which is labeled as a "limited edition" release. That version comes in a digipak case with a compartment in which a "handwritten lyrics" insert is contained. The far more rare UK limited edition release features covers that would later appear on the Crucify EP which was released in the United States.

The Four Seasons (Vivaldi)

The Four Seasons (Italian: Le quattro stagioni) is a group of four violin concerti by Italian composer Antonio Vivaldi, each of which gives a musical expression to a season of the year. They were written about 1723 and were published in 1725 in Amsterdam, together with eight additional violin concerti, as Il cimento dell'armonia e dell'inventione ("The Contest Between Harmony and Invention").

The Four Seasons is the best known of Vivaldi's works. Unusually for the time, Vivaldi published the concerti with accompanying poems (possibly written by Vivaldi himself) that elucidated what it was about those seasons that his music was intended to evoke. It provides one of the earliest and most-detailed examples of what was later called program music—music with a narrative element.

Vivaldi took great pains to relate his music to the texts of the poems, translating the poetic lines themselves directly into the music on the page. In the middle section of the Spring concerto, where the goatherd sleeps, his barking dog can be marked in the viola section. Other natural occurrences are similarly evoked. Vivaldi separated each concerto into three movements, fast-slow-fast, and likewise each linked sonnet into three sections. His arrangement is as follows: