Wilson's disease

Wilson's disease also called Wilson disease or hepatolenticular degeneration is an autosomal recessive genetic disorder in which copper accumulates in tissues; this manifests as neurological or psychiatric symptoms and liver disease. It is treated with medication that reduces copper absorption or removes the excess copper from the body, but occasionally a liver transplant is required.

The condition is due to mutations in the Wilson disease protein (ATP7B) gene. A single abnormal copy of the gene is present in 1 in 100 people, who do not develop any symptoms (they are carriers). If a child inherits the gene from both parents, the child may develop Wilson's disease. Symptoms usually appear between the ages of 6 and 20 years, but cases in much older people have been described. Wilson's disease occurs in 1 to 4 per 100,000 people. It is named after Samuel Alexander Kinnier Wilson (1878–1937), the British neurologist who first described the condition in 1912.

Signs and symptoms

Wilson

Wilson may refer to:

Name

Leaders

Places

Australia

Canada

Poland

United Kingdom

United States of America

Wilson's (department store)

Wilson's is a full line department store, based in Greenfield, Massachusetts. It first opened in 1882.

The original business, known as the Boston Store, was owned and operated by the White Brothers from 1882 to 1896. Its original frontage was only 25 feet, but it thrived and doubled in size. In 1896 John Wilson, from Scotland, bought the store from the Whites and renamed it the John Wilson Company. He enlarged the store by adding a second floor, a grand double staircase in the center, and a grocery department on the lower level. The new store even had a horse-drawn delivery service, with a livery stable on the premises.

In 1929, R. Stanley Reid of the former Boston Store in North Adams and George L. Willis of the then Wallace Company in Pittsfield together purchased the John Wilson Company store from the Wilson family. The Reid family owned the business after Mr. Willis’s death in 1941. Robert S. Reid, Jr. served as President of Wilson’s from the time of his father’s death in 1961 until his retirement in 1990. During his tenure he expanded the second floor and added a third floor into space once occupied by the Greenfield Hotel.

Kendal Mint Cake

Kendal Mint Cake is a glucose-based confection flavoured with peppermint. It originates from Kendal in Cumbria, England. Kendal Mint Cake is popular among climbers and mountaineers, especially those from the United Kingdom, as a source of energy.

History

Kendal Mint Cake is based on a traditional recipe known as mint cake, peppermint tablet and various other similar names. Kendal Mint Cake is well known to mountaineers and explorers for its high energy content. There are currently three companies that still produce Kendal mint cake in Kendal. The origin of the Mint cake is allegedly from a batch of Peppermint creams that went wrong. The mixture was left overnight and the solidified 'mint cake' was discovered in the morning.

Romney's

Romney's was founded in 1918 and used an old recipe to create Mint Cake. This Mint Cake was sold in Kendal and sent by train to other areas of the north west for sale. In 1987, Romney's bought Wiper's Mint Cake from Harry Wiper, who had inherited ownership of Wiper's in 1960 when his father died.