In 1892, he was appointed lecturer at Royal Veterinary and Agricultural University and later became professor of botany and plant physiology. He taught plant physiology. His most well-known research concerned so-called pure lines of the self-fertile common bean. He was able to show that even in populationshomozygous for all traits, i.e. without genetic variation, seed size followed a normal distribution. This was attributable to resource provision to the mother plant and to the position of seeds in pods and of pods on the plant. This led him to coin the terms phenotype and genotype.