Wheatfield Road begins at an intersection with US 15 Bus. within Gettysburg National Military Park in Cumberland Township, where the road continues west as Millerstown Road. From here, it heads east-southeast as a two-lane undivided road, heading through fields in the park. The road continues into wooded areas with some fields, passing to the north of Little Round Top. Wheatfield Road comes to an end at an intersection with PA 134 in the community of Round Top, where the road continues east as Blacksmith Shop Road to Baltimore Pike.