Troponin C

Troponin C is a part of the troponin complex. It contains four calcium-binding EF hands, although different isoforms may have fewer than four functional calcium-binding subdomains. It is a component of thin filaments (along with actin and tropomyosin). It contains an N lobe and a C lobe. The C lobe serves a structural purpose and binds to the N domain of troponin I (TnI). The C lobe can bind either Ca²⁺ or Mg²⁺. The N lobe, which binds only Ca²⁺, is the regulatory lobe and binds to the C domain of troponin I after calcium binding.

The tissue specific subtypes are:

Slow troponin C, TNNC1 (3p21.3-p14.3, Online 'Mendelian Inheritance in Man' (OMIM) 191040)

Fast troponin C, TNNC2 (20q12-q13.11, Online 'Mendelian Inheritance in Man' (OMIM) 191039)

External links

Troponin C at the US National Library of Medicine Medical Subject Headings (MeSH)

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Tournament of Champions (debate)

The Tournament of Champions (TOC) is a national high school debate tournament held at the University of Kentucky every year on the last weekend in April. The Tournament is considered the national championship of the “National Circuit,” with debaters having to apply to compete. It is considered the most prestigious and competitive American high school debate tournament. The tournament uses a bid system, in which placing high enough in certain, nationally or regionally respected tournaments earns debaters a bid, with at least 2 bids needed to compete. In addition to this, competitors can automatically qualify by placing high enough at last year’s tournament (or one of the two other national tournaments) or by getting accepted as an at large entry.

The tournament was created by Dr. J.W. Patterson, the former director of debate at the University of Kentucky. Incepted in 1972, it serves as the pinnacle of high school debate, allowing the best debaters in the United States to compete without other, less experienced debaters affecting the rankings. The Tournament currently holds competition in policy debate, Lincoln–Douglas debate, public forum debate, and Congressional Debate.

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Rule (surname)

Rule is a surname. Notable people with the name include:

Albert Leroy Rule, World War I documentary film producer & director

Ann Rule (1935–2015), American true crime writer.

Bert L. Rule (1891–1878), Popular music composer & arranger

Bob Rule (born 1944), American basketball player

Christopher Rule (1895–1983), American comic book artist

Elton Rule (1916–90), American television executive

Gilbert Rule (c. 1629–1701), Principal of Edinburgh University

Glenn Rule (born 1989), English soccer player

Ja Rule (born 1976), American rapper, singer and actor

Jack Rule, Jr. (born 1938), American professional golfer

Jane Rule (1931–2007), Canadian writer

Janice Rule (1931–2003), American actress

Margaret Rule (1928-2015), English underwater archaeologist

Stan Rule (1924-2007), Australian rules footballer

Stephen Rule (born 1952), English Rugby Union and Rugby League player and coach

Wendy Rule, Australian musical artist

William Rule (American editor) (1839–1928), American newspaper editor and politician

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Ruler

A ruler, sometimes called a rule or line gauge, is an instrument used in geometry, technical drawing, printing, engineering and building to measure distances or to rule straight lines. The ruler is a straightedge which may also contain calibrated lines to measure distances.

Types

Rulers have long been made of different materials and in a wide range of sizes. Some are wooden. Plastics have also been used since they were invented; they can be molded with length markings instead of being scribed. Metal is used for more durable rulers for use in the workshop; sometimes a metal edge is embedded into a wooden desk ruler to preserve the edge when used for straight-line cutting. 12 inches or 30 cm in length is useful for a ruler to be kept on a desk to help in drawing. Shorter rulers are convenient for keeping in a pocket. Longer rulers, e.g., 18 inches (45 cm) are necessary in some cases. Rigid wooden or plastic yardsticks, 1 yard long and meter sticks, 1 meter long, are also used. Classically, long measuring rods were used for larger projects, now superseded by tape measure or laser rangefinders.

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One percent

One percent (or 1%) may refer to:

Groups of people

The wealthiest 1% of people in a country (from "We are the 99%" that came from the Occupy Movement)

One Percenter, a term for a member of an outlaw motorcycle club derived from the statement "99% of motorcyclists are law-abiding citizens"

One Percent for the Planet, an international organization

1%Club, a non profit group using the Internet to help those in developing countries

Entertainment

The One Percent (film), a 2006 documentary about the growing wealth gap between America's wealthy elite and the citizenry on the whole

The One Percent (TV series) an upcoming American television series that will air on Starz

The One Percent Doctrine, a nonfiction book by Ron Suskind

1% of Anything, a South Korean TV drama

"1%" (South Park), an episode of South Park

Other uses

1% rule (Internet culture) that describes levels of contribution in online forums

1% rule (aviation medicine) that describes a risk threshold for medical incapacitation

1% Milk - see fat content of milk

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TOC

Documents

Organisations

Places

Science and technology

Troponin C

See also

External links

Tournament of Champions (debate)

Rule (surname)

Ruler

Types

One percent

Groups of people

Entertainment

Other uses

Podcasts:

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