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WASL (gene)
Neural Wiskott-Aldrich syndrome protein is a protein that in humans is encoded by the WASL gene.
The Wiskott-Aldrich syndrome (WAS) family of proteins share similar domain structure, and are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton. The presence of a number of different motifs suggests that they are regulated by a number of different stimuli, and interact with multiple proteins. Recent studies have demonstrated that these proteins, directly or indirectly, associate with the small GTPase, Cdc42, known to regulate formation of actin filaments, and the cytoskeletal organizing complex, Arp2/3. The WASL gene product is a homolog of WAS protein, however, unlike the latter, it is ubiquitously expressed and shows highest expression in neural tissues. It has been shown to bind Cdc42 directly, and induce formation of long actin microspikes.
According to one study, mouse DAB1 regulates actin cytoskeleton through N-WASP.
Interactions
Wasl
Wasl is a village in west-central Yemen. It is located in the San‘a’ Governorate.
External links
Coordinates: 15°03′N 43°40′E / 15.050°N 43.667°E
WASL
WASL may refer to:
WASL (FM)
Coordinates: 36°6′0.00″N 89°29′12.00″W / 36.1000000°N 89.4866667°W
WASL (100.1 FM, "Jack FM") is a radio station broadcasting a variety hits format. Licensed to Dyersburg, Tennessee, USA, the station is currently owned by Burks Broadcasting, through licensee Dr Pepper Pepsi-Cola Bottling Company of Dyersburg, LLC (dba Burks Beverage).
History
On March 5, 2015 WASL changed their format from mainstream rock (branded as "SL100") to variety hits, branded as "100 Jack FM".
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