S.S.D. Casarano Calcio is an Italian association football club located in Casarano, Apulia. It currently plays in Promozione Apulia.
The club was founded in 1927 playing also in Serie C1 for 20 seasons.
The club was refounded in 2006 as A.S.D. Virtus Casarano, but in summer 2012 it does not join in Serie D.
Immediately after on 24 July 2012, the club was again refounded by Eugenio Filograna as S.S.D. Casarano Calcio and was relocated in Promozione Apulia.
Its colors are red-azure.
Casarano is a town and sixth most populous comune in the Italian province of Lecce, in the Apulia region of South-East Italy. The town's economy is mostly agriculture-based, with olive oil being the main product. The Church of Santa Maria Della Croce is one of the oldest Christian sites in the world. The population as of December 2004 was 20,544. It is twinned with Charleroi, Belgium.