Urocanase (also known as imidazolonepropionate hydrolase or urocanate hydratase) is the enzyme that catalyzes the second step in the degradation of histidine, the hydration of urocanate into imidazolonepropionate.
Inherited deficiency of urocanase leads to elevated levels of urocanic acid in the urine, a condition known as urocanic aciduria.
Urocanase is found in some bacteria (gene hutU), in the liver of many vertebrates and has also been found in the plant Trifolium repens (white clover). Urocanase is a protein of about 60 Kd, it binds tightly to NAD+ and uses it as an electrophil cofactor. A conserved cysteine has been found to be important for the catalytic mechanism and could be involved in the binding of the NAD+.
You, you are feeling the hate of your girl
While the television is glad
There is a stupid face without expression
Like in a mahlerian symphony
And today the sun is very fine
The air is very light
While you are like a big shit
And the air is light again
WHEN YOUR EYES ARE FULL
WHEN THE COLOUR OF YOUR LIFE
IS LIKE A BORING MORNING
WITHOUT A SWEET CONTRETEMPS
Take your notes and close your eyes tonight
While the television is glad
Now, you are the king of all the things
Like in a mahlerian symphony
And today the sun is very fine
The air is very light
While you are like a big shit
And the air is light again
WHEN YOUR EYES ARE FULL
WHEN THE COLOUR OF YOUR LIFE
IS LIKE A BORING MORNING
WITHOUT A SWEET CONTRETEMPS
JUST TRY AND HIT ME
AND MAKE A BETTER USE OF YOUR NOTES
BECAUSE THE MUSIC IS LIKE A GUN-SHOT