Ukrain

Ukrain (Ukrainian: Україн; also called celandine) is the trademarked name of a semi-synthetic substance derived from the plant Chelidonium majus and promoted as a drug to treat cancer and viral infections, including HIV and hepatitis. It was created in 1978, by a Ukrainian chemist Vasyl Novytskyi. Ukrain is named after the nation of Ukraine and is produced by an Austrian company Nowicky Pharma.

According to the American Cancer Society and the Memorial Sloan-Kettering Cancer Center, there is no evidence that Ukrain is an effective cancer treatment.

Evidence

In 2005, Edzard Ernst led a review into evidence of the effectiveness of Ukrain. Although the review found evidence suggesting the drug was effective, it also concluded that "numerous caveats prevent a positive conclusion". Commenting on the review some years later, Ernst wrote on his blog that the results they were examining had seemed "too good to be true" – and on investigation the trials were very small in size, often seemed to include Novytskyi himself, and had significant methodological flaws. However, despite the cautious conclusion given, "this article became much cited. ... [Novytskyi] must have been delighted".