USS Biscayne (AVP-11), later AGC-18, was a United States Navy Barnegat-class seaplane tender in commission as a seaplane tender from 1941 to 1943 and as an amphibious force flagship from 1943 to 1946. She saw service during World War II. Transferred to the United States Coast Guard after the war, she was in commission as the Coast Guard cutter USCGC Dexter (WAGC-385), later WAVP-385 and WHEC-385, from 1946 to 1952 and from 1958 to 1968.
Biscayne was laid down on 27 October 1939 at Puget Sound Navy Yard in Bremerton, Washington. She was launched on 23 May 1941, sponsored by Mrs. A. M. Charleton, and commissioned on 3 July 1941 with Lieutenant Commander C. C. Champion, Jr., in command.
Following her shakedown cruise, Biscayne joined the Atlantic Fleet and operated out of Boston, Massachusetts, on patrol and plane guard missions from 7 December 1941 until 27 May 1942. For the next four months she served as a seaplane tender and communications ship in Newfoundland and Greenland waters.