The main event was a UFC & Pride FC middleweight title unification match between UFC middleweight champion Anderson Silva and PRIDE FC welterweight champion Dan Henderson.
A welterweight matchup between Jon Fitch and Akihiro Gono was originally scheduled, but Gono was forced to withdraw after suffering a hand injury in training. Gono was replaced by Chris Wilson. The Fitch/Gono match up was eventually rescheduled for UFC 94.