U-50488

U-50488 is a drug which acts as a highly selective κ-opioid agonist, but without any μ-opioid antagonist effects. It has analgesic, diuretic and antitussive effects, and reverses the memory impairment produced by anticholinergic drugs. U-50488 was one of the first selective kappa agonists invented and research on its derivatives has led to the development of a large family of related compounds.

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References

German submarine U-50

U-50 may refer to one of the following German submarines:

German submarine U-50 (1939)

German submarine U-50 was a Type VIIB U-boat of Nazi Germany's Kriegsmarine during World War II. Ordered on 21 November 1936, she was laid down as yard number 585 at the yards of Friedrich Krupp Germaniawerft AG in Kiel on 3 November 1938. She was launched on 1 November 1939 and commissioned on 12 December 1939 by Kapitänleutnant (Kptlt.) Max-Hermann Bauer, who was the sole commander of the boat. In her short career she conducted only two patrols, both as part of the 7th U-boat Flotilla. In this time she succeeded in sinking four ships, totalling 16,089 gross register tons (GRT).

Design

German Type VIIB submarines were preceded by the shorter Type VIIA submarines. U-50 had a displacement of 753 tonnes (741 long tons) when at the surface and 857 tonnes (843 long tons) while submerged. She had a total length of 66.50 m (218 ft 2 in), a pressure hull length of 48.80 m (160 ft 1 in), a beam of 6.20 m (20 ft 4 in), a height of 9.50 m (31 ft 2 in), and a draught of 4.74 m (15 ft 7 in). The submarine was powered by two Germaniawerft F46 four-stroke, six-cylinder supercharged diesel engines producing a total of 2,800 to 3,200 metric horsepower (2,060 to 2,350 kW; 2,760 to 3,160 shp) for use while surfaced, two AEG GU 460/8-276 double-acting electric motors producing a total of 750 metric horsepower (550 kW; 740 shp) for use while submerged. She had two shafts and two 1.23 m (4 ft) propellers. The boat was capable of operating at depths of up to 230 metres (750 ft).