Alpha-3 beta-4 nicotinic receptor

The alpha-3 beta-4 nicotinic receptor, also known as the α₃β₄ receptor, is a type of nicotinic acetylcholine receptor, consisting of α₃ and β₄ subunits. It is located in the autonomic ganglia and adrenal medulla, where activation yields post- and/or presynaptic excitation.

As with other nicotinic acetylcholine receptors, the α₃β₄ receptor is pentameric [(α₃)_m(β₄)_n where m + n = 5]. The exact subunit stoichiometry is not known and it is possible that more than one functional α₃β₄ receptor assembles in vivo with varying subunit stoichiometries.

Ligands

Agonists

Antagonists

Competitive

Noncompetitive