Tropane alkaloid

Tropane alkaloids are a class of bicyclic [3.2.1] alkaloids and secondary metabolites that contain a tropane ring in their chemical structure. Tropane alkaloids occur naturally in many members of the plant family Solanaceae. Some tropane alkaloids have pharmacological properties and can act as anticholinergics or stimulants.

Anticholinergics

Anticholinergic drugs and deliriants:

Atropine, racemic hyoscyamine, from the deadly nightshade (Atropa belladonna)

Hyoscyamine, the levo-isomer of atropine, from henbane (Hyoscamus niger) and mandrake (Mandragora officinarum)

Scopolamine, from henbane and Datura species (Jimson weed)

All three acetylcholine-inhibiting chemicals can also be found in the leaves, stems, and flowers in varying, unknown amounts in Brugmansia (Angel Trumpets or Devil's Weed), a relative of Datura.

Stimulants

Stimulants and cocaine-related alkaloids:

Cocaine, from Erythroxylum coca

Ecgonine, a precursor and metabolite of cocaine

Benzoylecgonine, a metabolite of cocaine

This page contains text from Wikipedia, the Free Encyclopedia - https://wn.com/Tropane_alkaloid

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Tropane alkaloid

Anticholinergics

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