Paclitaxel
Paclitaxel is a drug used to treat ovarian, breast, lung, pancreatic and other cancers. It and docetaxel represent the taxane family of drugs. Paclitaxel's mechanism of action involves interference with the normal breakdown of microtubules during cell division.
Common side effects include: hair loss, muscle and joint pains, and diarrhea, among others. It results in a greater risk of infections which can be potentially serious. Use during pregnancy often results in problems in the infant.
Paclitaxel was discovered beginning in 1962 as a result of a U.S. National Cancer Institute-funded screening program; being isolated from the bark of the Pacific yew, Taxus brevifolia, thus its name "taxol". Developed commercially by Bristol-Myers Squibb, the generic name has changed to "paclitaxel" with a trademark becoming Taxol. Other trademarks include Abraxane. Clinicians sometimes use the abbreviation "PTX" for paclitaxel, which is discouraged, because it is not a unique identifier.
Paclitaxel is on the World Health Organization's List of Essential Medicines, the most important medication needed in a basic health system. There was initially concern over the environmental impact of its initial sourcing from the slow growing Pacific yew. In addition, both the assignment of rights to Bristol-Myers Squibb and the product name were subject to public debate and Congressional hearings.
Podcasts:
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by Mansun
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by A Hope For Home
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by Aziel
Taxlo$$
by: MansunHe'll be your taxloss lover from Liverpool
Taxloss lover if the truth be told
Taxloss lover still lives in the war
Taxloss lover touching 74
Ah, come back to me
We want your money, taxloss
Ah, come back to me
We want your money, taxloss
We think you are stupid
We give you money 'cos our assets are fluid yeah
We'll sell you down the river
Just remember that we said we'd deliver you
Sign on the line and we'll give you the money
And then you'll be mine and we'll fly somewhere sunny
And you'll quibble that our drivel seems unsatifactory
You're a taxloss, come back to me
We want your money, taxloss
He'll be your taxloss lover and his name is Bert
Your taxloss lover and he's always a flirt
Your taxloss lover's into kinky sex
Your taxloss lover wears a cracking dress
Sign on the line and we'll give you the money
And then you'll be mine and we'll fly somewhere sunny
You'll quibble that our drivel seems unsatifactory
We're a taxloss, come back to me
We want your money, taxloss
Sign on the line and we'll give you the money
And then you'll be mine and we'll fly somewhere sunny
And you'll quibble that our drivel seems unsatifactory
A taxloss, come back to me
We want your money, taxloss
Taxloss, mod rock
Junk pop, chart hop
Mop top, swap shop
Who'd you nick your cliche off?