Toxic! was a British weekly comic book published by Apocalypse Ltd. A total of 31 issues were published from March 28-October 24, 1991.
Toxic! was the idea of Pat Mills, Kevin O'Neill, Mike McMahon, John Wagner and Alan Grant. The aim was to provide creators an outlet for their work to be published with them retaining the rights and control of their work. This was in contrast to 2000 AD, which Mills had also launched in 1977. Toxic! was to be the main rival of 2000 AD, and Toxic! would be in full colour throughout as opposed to 2000AD, which was still mainly published in black and white.
Toxic! was published by Apocalypse Ltd, an offshoot of Neptune Distribution based in South Wigston, Leicester. Neptune also owned Trident Comics which printed black and white comics by mainly new, unpublished creators.
The first title released by Apocalypse was a Marshal Law special titled Kingdom of the blind published in October 1990. This was followed by the first issue of Toxic! in March 1991. Toxic! was initially dominated by Mills (Mills had rejected two of John Wagner's proposals, Button Man and Al's Baby for not fitting in with his vision for the comic. These two strips later appeared in 2000 AD and the Judge Dredd Megazine respectively). His Marshal Law strip was seen as the flagship title and a character to perhaps rival Judge Dredd. Mills also wrote Accident Man (with Tony Skinner) and Muto-Maniac in the first issue, which was rounded out by a short strip by Alan Grant and Simon Bisley.
Toxicity is the degree to which a substance can damage an organism. Toxicity can refer to the effect on a whole organism, such as an animal, bacterium, or plant, as well as the effect on a substructure of the organism, such as a cell (cytotoxicity) or an organ such as the liver (hepatotoxicity). By extension, the word may be metaphorically used to describe toxic effects on larger and more complex groups, such as the family unit or society at large.
A central concept of toxicology is that effects are dose-dependent; even water can lead to water intoxication when taken in too high a dose, whereas for even a very toxic substance such as snake venom there is a dose below which there is no detectable toxic effect. Toxicity is species-specific, making cross-species analysis problematic. Newer paradigms and metrics are evolving to bypass animal testing, while maintaining the concept of toxicity endpoints.
There are generally three types of toxic entities; chemical, biological, and physical:
Toxic is the fifth studio album by Japanese rock band the Gazette. It was released on October 5, 2011 in Japan and includes four singles: "Shiver", "Red", "Pledge", and "Vortex". The album scored number 3 on the Oricon Daily Charts and number 6 on the Oricon Weekly Charts, selling 25,412 copies in its first week.
Wiley may refer to:
John Wiley & Sons, Inc., also referred to as Wiley (NYSE: JW.A), is a global publishing company that specializes in academic publishing and markets its products to professionals and consumers, students and instructors in higher education, and researchers and practitioners in scientific, technical, medical, and scholarly fields. The company produces books, journals, and encyclopedias, in print and electronically, as well as online products and services, training materials, and educational materials for undergraduate, graduate, and continuing education students.
Founded in 1807, Wiley is also known for publishing For Dummies. As of 2012, the company had 5,100 employees and a revenue of $1.8 billion.
Wiley was established in 1807 when Charles Wiley opened a print shop in Manhattan. The company was the publisher of such 19th century American literary figures as James Fenimore Cooper, Washington Irving, Herman Melville, and Edgar Allan Poe, as well as of legal, religious, and other non-fiction titles. Wiley later shifted its focus to scientific, technical, and engineering subject areas, abandoning its literary interests.
David Wiley Miller (born April 15, 1951, Burbank, California), an American cartoonist whose work is characterized by wry wit and trenchant social satire, is best known for his comic strip Non Sequitur, which he signs Wiley. Non Sequitur is the only cartoon to win National Cartoonists Society Divisional Awards in both the comic strip and comic panel categories, and Miller is the only cartoonist to win an NCS Divisional Award in his first year of syndication.
A California native, Wiley studied art at Virginia Commonwealth University and worked for several Hollywood educational film studios before relocating to North Carolina in 1976 to work as an editorial cartoonist and staff artist for the Greensboro News & Record. Fenton (1982) was his first syndicated strip. In 1985, he was hired as an editorial cartoonist at the San Francisco Examiner.
In 1991, Wiley launched his popular Non Sequitur strip, eventually syndicated to 700 newspapers. In 1994, Miller pioneered the use of process color in comic strips, and developed a format in 1995 that allows one cartoon to be used in two different ways for both panel dimensions and strip dimensions.