Toxic!
Toxic! was a British weekly comic book published by Apocalypse Ltd. A total of 31 issues were published from March 28-October 24, 1991.
History
Toxic! was the idea of Pat Mills, Kevin O'Neill, Mike McMahon, John Wagner and Alan Grant. The aim was to provide creators an outlet for their work to be published with them retaining the rights and control of their work. This was in contrast to 2000 AD, which Mills had also launched in 1977. Toxic! was to be the main rival of 2000 AD, and Toxic! would be in full colour throughout as opposed to 2000AD, which was still mainly published in black and white.
Toxic! was published by Apocalypse Ltd, an offshoot of Neptune Distribution based in South Wigston, Leicester. Neptune also owned Trident Comics which printed black and white comics by mainly new, unpublished creators.
The first title released by Apocalypse was a Marshal Law special titled Kingdom of the blind published in October 1990. This was followed by the first issue of Toxic! in March 1991. Toxic! was initially dominated by Mills (Mills had rejected two of John Wagner's proposals, Button Man and Al's Baby for not fitting in with his vision for the comic. These two strips later appeared in 2000 AD and the Judge Dredd Megazine respectively). His Marshal Law strip was seen as the flagship title and a character to perhaps rival Judge Dredd. Mills also wrote Accident Man (with Tony Skinner) and Muto-Maniac in the first issue, which was rounded out by a short strip by Alan Grant and Simon Bisley.
Toxicity
Toxicity is the degree to which a substance can damage an organism. Toxicity can refer to the effect on a whole organism, such as an animal, bacterium, or plant, as well as the effect on a substructure of the organism, such as a cell (cytotoxicity) or an organ such as the liver (hepatotoxicity). By extension, the word may be metaphorically used to describe toxic effects on larger and more complex groups, such as the family unit or society at large.
A central concept of toxicology is that effects are dose-dependent; even water can lead to water intoxication when taken in too high a dose, whereas for even a very toxic substance such as snake venom there is a dose below which there is no detectable toxic effect. Toxicity is species-specific, making cross-species analysis problematic. Newer paradigms and metrics are evolving to bypass animal testing, while maintaining the concept of toxicity endpoints.
Types of toxicity
There are generally three types of toxic entities; chemical, biological, and physical:
Toxic (album)
Toxic is the fifth studio album by Japanese rock band the Gazette. It was released on October 5, 2011 in Japan and includes four singles: "Shiver", "Red", "Pledge", and "Vortex". The album scored number 3 on the Oricon Daily Charts and number 6 on the Oricon Weekly Charts, selling 25,412 copies in its first week.
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Guanajuato
Guanajuato (Spanish pronunciation: [gwanaˈxwato]), officially Free and Sovereign State of Guanajuato (Spanish: Estado Libre y Soberano de Guanajuato), is one of the 31 states which, with the Federal District, are the 32 Federal entities of Mexico. It is divided into 46 municipalities and its capital city is Guanajuato. The largest city in the state is León.
It is located in North-Central Mexico. It is bordered by the states of Jalisco to the west, Zacatecas to the northwest, San Luis Potosí to the north, Querétaro to the east and Michoacán to the south. It covers an area of 30,608 km2 (11,818 sq mi).
Guanajuato is located between the arid north of the country and the lusher south, and it is geographically part of the Trans-Mexican Volcanic Belt, the Mexican Plateau and the Sierra Madre Oriental. It was initially settled by the Spanish in the 1520s due to mineral deposits found around the now capital city of Guanajuato, but areas such as the Bajío region also became important for agriculture and livestock. Mining and agriculture have been the traditional mainstays of the state's economy, but today, about 30% of the state's GDP is accounted for by industry, which includes metals, automobiles, leather goods, processed foods and more.
Ferrari 250 GTO
The Ferrari 250 GTO is a racing GT car which was produced by Ferrari from 1962 to 1964 for homologation into the FIA's Group 3 Grand Touring Car category. In May 2012 the 1962 250 GTO made for Stirling Moss became the world's most expensive car in history, selling in a private transaction for $38,115,000 to US communications magnate Craig McCaw. In October 2013, Connecticut-based collector Paul Pappalardo sold chassis number 5111GT to an unnamed buyer for a new record, somewhere within the $38 million range. The numerical part of its name denotes the displacement in cubic centimeters of each cylinder of the engine, whilst GTO stands for "Gran Turismo Omologato",Italian for "Grand Touring Homologated." When new, the GTO cost $18,000 in the United States, and buyers had to be personally approved by Enzo Ferrari and his dealer for North America, Luigi Chinetti.
In total, 39 250 GTOs were manufactured between 1962 and 1964. This includes 33 cars with 1962-63 bodywork (Series I), three cars with 1964 (Series II) bodywork similar to the Ferrari 250 LM and three "330 GTO" specials with a larger engine. Four of the older 1962-1963 (Series I) cars were retrofitted in 1964 with an updated (Series II) body.
GTO
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