Civilization: Beyond Earth

Sid Meier's Civilization: Beyond Earth is a turn-based strategy, 4X video game in the Civilization series developed by Firaxis Games, published by 2K Games and released for Microsoft Windows on October 24, 2014, the Mac App Store on November 27, 2014 and for Linux on December 18, 2014. A spiritual successor to Alpha Centauri, Beyond Earth shares much of that game's development team, as well as some concepts which were introduced in the 1999 title. The game's setting is unique to the Civilization series in that it takes place in the future, with mankind traveling through space and founding colonies on extraterrestrial planets after Earth becomes uninhabitable due to an undescribed disaster known as "the Great Mistake".

An expansion pack, titled Rising Tide, was released on October 9, 2015.

Gameplay

Beyond Earth is a turn-based strategy game played on a hexagonal-based grid, iterating the ideas and building upon the engine of its predecessor, Civilization V. Co-lead designer David McDonough described the relationship between the two games by saying "The bones of the experience are very much recognisably Civ. The idea of the cities, city-base progression, leaders, the passage of time, tile-based, turn-based, building improvements, technologies. A lot of them are very familiar themes to the Civ player."

X-linked spinal muscular atrophy type 2

X-linked spinal muscular atrophy type 2 (SMAX2, XLSMA), also known as arthrogryposis multiplex congenita X-linked type 1 (AMCX1), is a rare neurological disorder involving death of motor neurons in the anterior horn of spinal cord resulting in generalised muscle wasting (atrophy). The disease is caused by a mutation in UBA1 gene and is passed in a X-linked recessive manner by carrier mothers to affected sons.

Affected babies have general muscle weakness, weak cry and floppy limbs; consequently, the condition is usually apparent at or even before birth. Symptoms resemble the more severe forms of the more common spinal muscular atrophy (SMA); however, SMAX2 is caused by a different genetic defect and only genetic testing can correctly identify the disease.

The disorder is usually fatal in infancy or early childhood due to progressive respiratory failure, although survival into teenage years have been reported. As with many genetic disorders, there is no known cure to SMAX2. Appropriate palliative care may be able to increase quality of life and extend lifespan.

Spinal and bulbar muscular atrophy

Spinal and bulbar muscular atrophy (SBMA), also known as spinobulbar muscular atrophy, bulbo-spinal atrophy, X-linked bulbospinal neuropathy (XBSN), X-linked spinal muscular atrophy type 1 (SMAX1), Kennedy's disease (KD), and many other names — is a debilitating neurodegenerative disorder resulting in muscle cramps and progressive weakness due to degeneration of motor neurons in the brain stem and spinal cord.

The condition is associated with mutation of the androgen receptor (AR) gene and is inherited in an X-linked recessive manner. As with many genetic disorders, no cure is known, although research continues.

Because of its endocrine manifestations related to the impairment of the AR gene, SBMA can be viewed as a variation of the disorders of the androgen insensitivity syndrome (AIS). It is also related to other neurodegenerative diseases caused by similar mutations, such as Huntington's disease and the spinocerebellar ataxias.

Genetics

The androgen receptor gene that is mutated in SBMA is located on the X chromosome, and the effects of the mutation may be androgen-dependent, thus only males are fully affected. Females are rarely affected; female carriers tend to have a relatively mild expression of the disease if they show symptoms at all.

Tornø

Tornø (meaning Thorn Island) is a small island in the Odense Fjord, roughly 7 kilometres (4.3 mi) northeast of the city of Odense, in Kerteminde Municipality, Funen, Denmark. It covers an area of 21 hectares (52 acres) and is connected to the mainland by a 300 m (980 ft)-long causeway. The first tenant farmer on the island was Hans Eriksen in 1921.

For years the island could only be reached by riding or driving through the shallow waters but after Anders Jørgensen bought the island in 1922, he connected it to the mainland by road so that he could transport shells from the island. The link was completed in 1926. His shell crushing plant has long disappeared but the land is still farmed on Odense Fjord's only inhabited island. The original farm has long been replaced by a modern brick building. As of 2006 the island had a population of 3 people, with 4 people reported in 2014, although the island is inaccessible to the general public. It contains a narrow strip of salt marsh.

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Torn

Torn may refer to:

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Gaming

Torn (online game)

Torn, previously known as Torn City before the change to TORN, is a free, online text-based massive multiplayer online role-playing game (MMORPG) created by British online gaming entrepreneur Joe Chedburn. The game was launched in 2003. In 2010, over 24,000 people played daily, and over 1 million accounts existed in total.Torn is a virtual world based around gang violence. Like many RPGs, players start at the bottom of the ladder and make their way to the top by earning experience points. The game focuses on crimes and player versus player combat as a way of earning XP or experience points.

Torn uses the "freemium" business model: players can purchase in-game benefits in exchange for payments, which are termed "donations". The donations can be made by either PayPal, Bitcoins, Amazon or the recently resurrected mobile phone method. Another form of donation which was recently added was the subscription service. You are allowed to create a monthly subscription to Torn and you will receive a Donator Pack monthly, as well as a yearly subscription in which you will receive a Donator Pack lasting for a total of 267 days.