TIR

Tir, tir or TIR may mean:

  • The French term for Schützenfest, a target-shooting competition
  • Tir (month), the fourth month (the first month of summer) in the Iranian calendar
  • Tir, Iran, a village in North Khorasan Province, Iran
  • Occasional spelling of the Old Norse theonym Tyr
  • A woman thrall in Old Norse society
  • Abbreviations

  • Total Internal Reflection
  • Tigrinya language ISO 639 code
  • Tirupati Airport, the IATA airport code
  • Traumatic Incident Reduction, a form of psychotherapy
  • Translation Initiation Region, the starting point of translation of proteins.
  • Translocated intimin receptor, a receptor used by enteropathogenic Escherichia coli (EPEC).
  • The TIR Convention of road transportation (Transports Internationaux Routiers, International Road Transport)
  • Toll/Interleukin-1 receptor, the cytoplasmic domain of TLR-4
  • Total indicated runout, a measure of roundness or concentricity in the production of machined parts
  • Total indicator reading, a more general extrapolation of total indicated runout, applicable to other areas of metrology
  • Tir (receptor)

    Tir (translocated intimin receptor) is an essential component in the adherence of the enteropathogenic Escherichia coli (EPEC) and enterohemorraghic Escherichia coli to the cells lining the small intestine. To aid attachment, both EPEC and EHEC possess the ability to reorganise the host cell actin cytoskeleton via the secretion of virulence factors. These factors are secreted directly into the cells using a Type three secretion system. One of the virulence factors secreted is the Translocated Intimin Receptor (Tir). Tir is a receptor protein encoded by the espE gene which is located on the locus of enterocyte effacement (LEE) pathogenicity island in EPEC strains. It is secreted into the host cell membranes and acts as a receptor for intimin which is found on the bacterial surface. Once Tir binds intimin, the bacterium is attached to the enterocyte surface.

    Tir is also a receptor tyrosine kinase (RTK) that initiates its intimate adherence by inserting a hairpin orientation in the intestinal cell membrane to enable tight binding to intimin on the bacterial cell outer membrane. Upon phosphorylation, Tir activates condensation and polymerization of actin filaments under the bacterial cell to form a pedestal-like structure.

    Tir (month)

    Tir (Persian: تیر, Persian pronunciation: [tiːɾ]) is the fourth month of the Iranian calendar. It begins in June and ends in July of the Gregorian calendar. Tir has thirty-one days, spanning June and July in the Gregorian calendar.

    Tir is the first month of summer, and is followed by Mordad.

    Events

  • 14 - 1155 - United States Congress adopts the Declaration of Independence.
  • Deaths

  • 4 - 1392 - Taghi Rouhani, Iranian radio news anchor.
  • 22 - 1391 - Hamid Samandarian, Iranian film and theater director and translator.
  • 26 - 1390 - Rouhollah Dadashi, Iranian Powerlifter, Bodybuilder and Strongman.
  • 29 - 1391 - Mohammad Hassan Ganji, an Iranian meteorologist and academic.
  • References


    Podcasts:

    Týr

    ALBUMS

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    Latest News for: tir

    TIR transport service launched between China, Uzbekistan

    People Daily 09 Apr 2025
    This marks the official launch of Shenyang's first TIR cross-border road transport route connecting China, Kazakhstan and Uzbekistan, a new route that expands the assembly center's existing China-Russia transport network.

    TIR transport service launched between China, Uzbekistan (The Central People's Government of the People's Republic of China)

    Public Technologies 09 Apr 2025
    This marks the official launch of Shenyang's first TIR cross-border road transport route connecting China, Kazakhstan and Uzbekistan, a new route that expands the assembly center's existing China-Russia transport network.

    TIR London 1987

    Armstrong Economics 30 Mar 2025
    https.//www.armstrongeconomics.com/wp-content/uploads/2017/10/TIR-London-1987.mp4 ....

    TIR goes live in Iraq in breakthrough for Middle East trade and development (IRU - International Road Transport Union)

    Public Technologies 24 Mar 2025
    ) Iraq is set to reap the benefits of the global TIR transit system when it goes live next week in the country, marking a new era in international logistics and trade. The TIR system will become fully operational in Iraq from 1 April 2025.
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