 |
This article is an orphan, as few or no other articles link to it. Please introduce links to this page from related articles; suggestions may be available. (February 2009) |
Lymphoid-specific helicase is an enzyme that in humans is encoded by the HELLS gene.[1][2][3]
This gene encodes a lymphoid-specific helicase. Other helicases function in processes involving DNA strand separation, including replication, repair, recombination, and transcription. This protein is thought to be involved with cellular proliferation and may play a role in leukemogenesis. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.[3]
References [link]
- ^ Geiman TM, Durum SK, Muegge K (Feb 1999). "Characterization of gene expression, genomic structure, and chromosomal localization of Hells (Lsh)". Genomics 54 (3): 477–83. DOI:10.1006/geno.1998.5557. PMID 9878251.
- ^ Lee DW, Zhang K, Ning ZQ, Raabe EH, Tintner S, Wieland R, Wilkins BJ, Kim JM, Blough RI, Arceci RJ (Aug 2000). "Proliferation-associated SNF2-like gene (PASG): a SNF2 family member altered in leukemia". Cancer Res 60 (13): 3612–22. PMID 10910076.
- ^ a b "Entrez Gene: HELLS helicase, lymphoid-specific". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3070.
Further reading [link]
- Ohira M, Morohashi A, Nakamura Y et al. (2003). "Neuroblastoma oligo-capping cDNA project: toward the understanding of the genesis and biology of neuroblastoma". Cancer Lett. 197 (1–2): 63–8. DOI:10.1016/S0304-3835(03)00085-5. PMID 12880961.
- Andersson B, Wentland MA, Ricafrente JY et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. DOI:10.1006/abio.1996.0138. PMID 8619474.
- Hillier LD, Lennon G, Becker M et al. (1997). "Generation and analysis of 280,000 human expressed sequence tags". Genome Res. 6 (9): 807–28. DOI:10.1101/gr.6.9.807. PMID 8889549.
- Yu W, Andersson B, Worley KC et al. (1997). "Large-Scale Concatenation cDNA Sequencing". Genome Res. 7 (4): 353–8. DOI:10.1101/gr.7.4.353. PMC 139146. PMID 9110174. //www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139146.
- Strausberg RL, Feingold EA, Grouse LH et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. DOI:10.1073/pnas.242603899. PMC 139241. PMID 12477932. //www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241.
- Ota T, Suzuki Y, Nishikawa T et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. DOI:10.1038/ng1285. PMID 14702039.
- Sun LQ, Lee DW, Zhang Q et al. (2004). "Growth retardation and premature aging phenotypes in mice with disruption of the SNF2-like gene, PASG". Genes Dev. 18 (9): 1035–46. DOI:10.1101/gad.1176104. PMC 406293. PMID 15105378. //www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=406293.
- Deloukas P, Earthrowl ME, Grafham DV et al. (2004). "The DNA sequence and comparative analysis of human chromosome 10". Nature 429 (6990): 375–81. DOI:10.1038/nature02462. PMID 15164054.
- Yano M, Ouchida M, Shigematsu H et al. (2004). "Tumor-specific exon creation of the HELLS/SMARCA6 gene in non-small cell lung cancer". Int. J. Cancer 112 (1): 8–13. DOI:10.1002/ijc.20407. PMID 15305370.
- Gerhard DS, Wagner L, Feingold EA et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. DOI:10.1101/gr.2596504. PMC 528928. PMID 15489334. //www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=528928.
 |
This article on a gene on chromosome 10 is a stub. You can help Wikipedia by expanding it. |
https://wn.com/HELLS
Podcasts:
PLAYLIST TIME: