Taste receptor
A taste receptor is a type of receptor which facilitates the sensation of taste. When food or other substances enter the mouth, molecules interact with saliva and are bound to taste receptors in the oral cavity and other locations. Molecules which give a sensation of taste are considered "sapid".
Taste receptors are divided into two families:
Type 1, sweet, first characterized in 2001:TAS1R1 – TAS1R3
Type 2, bitter, first characterized in 2000:TAS2R1 – TAS2R50, and TAS2R60
Combinations of these receptors in dimers or other complexes contributes to different perceptions of taste.
Visual, olfactive, “sapictive” (the perception of tastes), trigeminal (hot, cool), mechanical, all contribute to the perception of taste. Of these, transient receptor potential cation channel subfamily V member 1 (TRPV1) vanilloid receptors are responsible for the perception of heat from some molecules such as capsaicin, and a CMR1 receptor is responsible for the perception of cold from molecules such as menthol, eucalyptol, and icilin.