Talkeetna (Dena'ina: K'dalkitnu) is a census-designated place (CDP) in Matanuska-Susitna Borough, Alaska, United States. It is part of the Anchorage, Alaska Metropolitan Statistical Area. At the 2010 census the population was 876.
Talkeetna is located at 62°18′41″N 150°5′13″W / 62.31139°N 150.08694°W (62.311397, -150.087053) at the confluence of three rivers, the Susitna, Chulitna and Talkeetna. Talkeetna began in 1916 when the area was chosen as a district headquarters for the Alaska Railroad. A post office opened as well as a sawmill, trading post, cigar store and other businesses as well as many cabins. In 1917, the residents encouraged the government to survey the lots on which their homes stood. In 1919, the railroad surveyed and auctioned 80 lots, 41 of which already had permanent structures on them. The average price at the sale was $14.25. Flightseeing, rafting, mountain biking, hiking, camping, fishing and hunting make up a large portion of the local economy. Talkeetna is a 2.5 hour drive from Anchorage, the largest city in Alaska. The core downtown area is classified as a National Historic Site, with buildings dating from the early 1900s including Nagley's General Store, Fairview Inn and the Talkeetna Roadhouse.
Talkeetna Depot is a freight and passenger railroad station in Talkeetna, Alaska. The station offers service for the Alaska Railroad's Denali Star and Aurora Winter Train routes.