Tus may refer to:
Tous son of Nowzar (Persian توس نوذر) is a mythological Iranian prince and hero from the Pishdadian-Dynasty, which deeds and adventures were told in Ferdowsi's Shahnameh.
Tous was a wise and brave man but also proud and pugnacious. And because of these characteristics he did not possess the king's divine glory (Middle Persian: khvarrah; Persian: farr) and was not elected by the other nobles of Iran as heir to his father King Nowzar. Instead, his cousin Zav became the new king of Iran and founder of the famous Kayanian dynasty. Nevertheless, Tous was a loyal vassal to the following kings Kai Kobad and Kai Kavoos and a great warrior defending Iran against her old arch-rival Turan, the land of the Turanians. Among the first and noblest knights of Iran he accompanied the king on several campaigns, and his coat of arms shows the device of a golden elephant as well as he and his kin wore golden shoes.
Tus, also known as terminus utilization substance, is a protein that binds to terminator sequences and acts as a counter-helicase when it comes in contact with an advancing helicase. The bound Tus protein effectively halts DNA polymerase movement. Tus helps end DNA replication in prokaryotes.
In E. coli, Tus binds to 10 closely related sites encoded in the chromosome. These sites bind 23 base-pairs. The 10 sites are called Ter sites, and are designated TerA, TerB, ..., TerJ. These binding sites are asymmetric, such that when a Tus-Ter complex (Tus protein bound to a Ter site) is encountered by a replication fork from one direction, the complex is dissociated and replication continues (permissive). But when encountered from the other direction, the Tus-Ter complex provides a much larger kinetic barrier and halts replication (non-permissive). The multiple Ter sites in the chromosome are oriented such that the two oppositely moving replication forks are both stalled in the desired termination region.
Sister love, why don't you break it up?
You got to let someone look into your heart
Sister love, how do you keep it up?
If you don't let no-one look into your heart
As a kid, you couldn't live it up
You were so serious but always so smart
As a kid, you couldn't keep it up
And we were never close, so much apart
Here comes the sun smiling
How long have you been blue?
There'd ever be a time for us to recapture
All the time we lose
There was a time when you were being so proud
Could have been anythin' that you aspired
There was a time when you were never around
When somethin' good happened, somethin' good happened right
So sister love, I'll help you off the ground
You got to let someone look into your heart
You got to turn this situation around
You got to turn this, turn it around
Here comes the sun smiling
How long have you been blue?
There'd ever be a time for us to recapture
All the time we lose
'Cause it's plain to see
A storm is not the weather
And I'm telling you girl
You'll look at them and smile
I'm telling you girl
You'll look at them and smile
7 days you should be givin' yourself
All your belongings, all that you treasure
7 weeks you think of nobody else
Is this what you want, is this what you are?
How did it come this far?
Here comes the sun smilin'
The only thing that's true
There'd ever be a time for us to recapture
All the time we lose
'Cause it's plain to see
A storm is not the weather
And I'm telling you girl
You'll look at them and smile
And I'm telling you girl
You'll look at them and smile
And I'm telling you girl
You'll look at them and smile
And I'm telling you girl