TSG

TSG can refer to:

Companies, groups and clubs

Technical Terms

List of Latin-script trigraphs

A number of trigraphs are found in the Latin script, most of these used especially in Irish orthography.

A

⟨aai⟩ is used in Dutch to write the sound /aːi̯/.

⟨abh⟩ is used in Irish to write the sound /əu̯/, or in Donegal, /oː/, between broad consonants.

⟨adh⟩ is used in Irish to write the sound /əi̯/, or in Donegal, /eː/, between broad consonants, or an unstressed /ə/ at the end of a word.

⟨aei⟩ is used in Irish to write the sound /eː/ between a broad and a slender consonant.

⟨agh⟩ is used in Irish to write the sound /əi̯/, or in Donegal, /eː/, between broad consonants.

⟨aim⟩ is used in French to write the sound /ɛ̃/ (/ɛm/ before a vowel).

⟨ain⟩ is used in French to write the sound /ɛ̃/ (/ɛn/ before a vowel). It also represents /ɛ̃/ in Tibetan Pinyin, where it is alternatively written än.

⟨aío⟩ is used in Irish to write the sound /iː/ between broad consonants.

⟨amh⟩ is used in Irish to write the sound /əu̯/, or in Donegal, /oː/, between broad consonants.

TSG101

Tumor susceptibility gene 101, also known as TSG101, is a human gene that encodes for a cellular protein of the same name.

Function

The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression.

The main role of ESCRT-I is to recognise ubiquitinated cargo via the UEV protein domain of the VPS23/TSG101 subunit. The assembly of the ESCRT-I complex is directed by the C-terminal steadiness box (SB) of VPS23, the N-terminal half of VPS28, and the C-terminal half of VPS37. The structure is primarily composed of three long, parallel helical hairpins, each corresponding to a different subunit. The additional domains and motifs extending beyond the core serve as gripping tools for ESCRT-I critical functions.

Group

Group may refer to:

Groups of people

In science and technology

In mathematics

In chemistry

In computing and the internet

Other uses in science and technology

Other uses

Stratigraphic unit

A stratigraphic unit is a volume of rock of identifiable origin and relative age range that is defined by the distinctive and dominant, easily mapped and recognizable petrographic, lithologic or paleontologic features (facies) that characterize it.

Units must be mappable and distinct from one another, but the contact need not be particularly distinct. For instance, a unit may be defined by terms such as "when the sandstone component exceeds 75%".

Lithostratigraphic units

Sequences of sedimentary and volcanic rocks are subdivided on the basis of their lithology. Going from smaller to larger in scale, the main units recognised are Bed, Member, Formation, Group and Supergroup.

Bed

A bed is a lithologically distinct layer within a member or formation and is the smallest recognisable stratigraphic unit. These are not normally named, but may be in the case of a marker horizon.

Member

A member is a named lithologically distinct part of a formation. Not all formations are subdivided in this way and even where they are recognized, they may only form part of the formation.

1994 Group

The 1994 Group was a coalition of smaller research-intensive universities in the United Kingdom, founded in 1994 to defend these universities' interests following the creation of the Russell Group by larger research-intensive universities earlier that year. The 1994 Group originally represented seventeen universities, rising to nineteen, and then dropping to eleven. The Group started to falter in 2012, when a number of high performing members left to join the Russell Group. The 1994 Group ultimately dissolved in November 2013.

Role

The group sought "to represent the views of its members on the current state and the future of higher education through discussions with the government, funding bodies, and other higher education interest groups" and "[made] its views known through its research publications and in the media".

University Alliance, million+, GuildHE and the Russell Group were its fellow university membership groups across the UK higher education sector.

Members

1994 Group position in league tables