TREM1
Triggering receptor expressed on myeloid cells 1 is a protein that in humans is encoded by the TREM1 gene.
Function
Monocyte/macrophage- and neutrophil-mediated inflammatory responses can be stimulated through a variety of receptors, including G protein-linked 7-transmembrane receptors (e.g., FPR1; MIM 136537), Fc receptors (see MIM 146790), CD14 (MIM 158120) and Toll-like receptors (e.g., TLR4; MIM 603030), and cytokine receptors (e.g., IFNGR1; MIM 107470). Engagement of these receptors can also prime myeloid cells to respond to other stimuli. Myeloid cells express receptors belonging to the Ig superfamily, such as TREM1, or to the C-type lectin superfamily. Depending on their transmembrane and cytoplasmic sequence structure, these receptors have either activating (e.g., KIR2DS1; MIM 604952) or inhibitory functions (e.g., KIR2DL1; MIM 604936).[supplied by OMIM]
Model organisms
Model organisms have been used in the study of TREM1 function. A conditional knockout mouse line called Trem1tm1(KOMP)Vlcg was generated at the Wellcome Trust Sanger Institute. Male and female animals underwent a standardized phenotypic screen to determine the effects of deletion. Additional screens performed: - In-depth immunological phenotyping
Podcasts:
-
by Dream High
-
by Dream High
B Class Life
by: Dream High[Seul]
I am a girl just a girl
Jinaganeun geol bwado moreuneun geol
Jeonhyeo yeppeujido anko nunnatgo
Pyeongbeomhagi geujieomneun saram
[JR]
I am a boy just a boy
Sumanheun boi junge geujeo han boi
Mwonga teukbyeolhan ge eopgo mueotdo
Naeseulge eomneun geureon saram
[All]
Urineun 'B' 'B' 'B' geup insaeng 'A' geubi doego sipeundae
Urineun bibi bijeongsangdeul jeongsange seogo sipeun
Urineun 'B' 'B' 'B' geup insaeng 'A' geubi doego sipeundae
Urineun bibi bijeongsangdeul jeongsange seogo sipeun
[Yoojin]
Byeolboril eomneun boril
Sseuldeeomneun sseul ttaeman gajyeotjyo
Bujireomneun ttambangulman jureukjureuk heulligo itjyo
[Hye Sung]
Dapdaphan nae mamboda deo dapdaphaehaneun nae juwiui
Saramdeurui pyojeongboda nakkaji jichyeogajyo
[All]
Urineun B B B geup insaeng A geubi doego sipeundae
Urineun bibi bijeongsangdeul jeongsange seogo sipeun
Urineun 'B' 'B' 'B' geup insaeng 'A' geubi doego sipeundae
Urineun bibi bijeongsangdeul jeongsange seogo sipeun
[Hye Sung And Hong Joo]
Eonjenga nae ane inneun nae teukbyeolhameul chajanae
Boyeojul nari isseulkkayo
Maeume eolma namji anheun nae kkumeul da irki jeone
Naege bichi bichul su isseulkkayo
[All]
Urineun 'B' 'B' 'B' geup insaeng 'A' geubi doego sipeundae
Urineun bibi bijeongsangdeul jeongsange seogo sipeun
Urineun 'B' 'B' 'B geup insaeng A geubi doego sipeundae
Urineun bibi bijeongsangdeul jeongsange seogo sipeun