Tremé (/trəˈmeɪ/ trə-MAY); is a neighborhood of the city of New Orleans. "Tremé" is often rendered as Treme, historically the neighborhood is sometimes called by its more formal French names of Faubourg Tremé; it is listed in the New Orleans City Planning Districts as Tremé / Lafitte when including the Lafitte Projects. Originally known as "Back of Town," urban planners renamed the neighborhood "Faubourg Tremé" in an effort to revitalize the historic area. A subdistrict of the Mid-City District Area, its boundaries as defined by the City Planning Commission are Esplanade Avenue to the east, North Rampart Street to the south, St. Louis Street to the west and North Broad Street to the north. It is one of the oldest neighborhoods in the city, and early in the city's history was the main neighborhood of free people of color. Historically a racially mixed neighborhood, it remains an important center of the city's African-American and Créole culture, especially the modern brass band tradition.
Triggering receptor expressed on myeloid cells 2 also known as TREM-2 is a protein that in humans is encoded by the TREM2 gene.
Monocyte/macrophage- and neutrophil-mediated inflammatory responses can be stimulated through a variety of receptors, including G protein-linked 7-transmembrane receptors (e.g., FPR1), Fc receptors, CD14 and Toll-like receptors (e.g., TLR4), and cytokine receptors (e.g., IFNGR1). Engagement of these receptors can also prime myeloid cells to respond to other stimuli. Myeloid cells express receptors belonging to the Immunoglobulin (Ig) superfamily, such as TREM2, or to the C-type lectin superfamily. Depending on their transmembrane and cytoplasmic sequence structure, these receptors have either activating (e.g., KIR2DS1) or inhibitory functions (e.g., KIR2DL1).
Homozygous mutations in TREM2 are known to cause rare, autosomal recessive forms of dementia with an early onset and presenting with or without bone cysts and fractures.
And no matter how many things I have
No one will ever love me your way
No matter what love invades my space
One things for sure
You won't be replaced
Oh oh oh oh singing
If you can't see the tears running down my eyes
I guess I gotta make the sun cry
If you can't see the tears running down my eyes
I guess I gotta make the sun cry
It hurts me just to see your name
And that tattoo runs right through my veins
My sister misses you the same
And it hurts me cuz I know she just can't say it
And what I would give to see your face yea
Where ever you are I pray your safe yea
Forgive me for my selfish ways yea
For I know that you're better off these days yea
Baby I miss you every time it rains
And no matter how bright the sun may shine
It never dries away the pain
Singing oh oh oh oh
Singing oh oh oh oh
And you're written all over me
So much so I can't believe
Your grandchildren are a sight to see
Every day there more of you and less of me
And what a cliché I know you're here
No fear I know you're near
And no matter how manny things I have
No one will ever love me your way
And no matter what love invades my space
One things for sure
You won't be replaced
Baby I miss you every time it rains
And no matter how bright the sun may shine
It will nerver dry away this pain
And I'm singing oh oh oh oh
And I'm singing oh oh oh oh
If you can't see the tears running down my eyes
I guess I gotta make the sun cry
If you can't see the tears running down my eyes
Shit I guess I gotta make the sun cry
Oh yea oh yea...
Oh yea oh yea...
Oh yea oh yea...
Momma I miss you every time it rains
No matter how bright the sun may shine
It will never dry away this pain
And I'm singing oh
And I'm singing oh oh oh oh
And I'm singing oh