TRAF3
TNF receptor-associated factor 3 is a protein that in humans is encoded by the TRAF3 gene.
Function
The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF receptor (TNFR) superfamily. This protein participates in the signal transduction of CD40, a TNFR family member important for the activation of the immune response. This protein is found to be a critical component of the lymphotoxin-beta receptor (LTbetaR) signaling complex, which induces NF-kappaB activation and cell death initiated by LTbeta ligation. Epstein-Barr virus encoded latent infection membrane protein-1 (LMP1) can interact with this and several other members of the TRAF family, which may be essential for the oncogenic effects of LMP1. Three alternatively spliced transcript variants encoding two distinct isoforms have been reported.
Interactions
TRAF3 has been shown to interact with:
Podcasts:
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by National
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by Suburban Legends
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by Insyderz
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by Alliswell
Trophy Wife
by: NationalNo nobody wants to be
no no one's lover
no matter what they say
lovers know they are the ones
who one day have to go
trophy wives
I know they wander
and find a young young man
trophy wives
I know they wander
one time you were a good rabbit
to all the girls
and all their lovely mothers
you tried a piece of everything
now nothing turns you on
trophy wives
I know they wander
and find a young young man
trophy wives
I know they wander
run run baby I don't feel alive
but I'm pretty and I'm pretty sure
I'm gonna be alright to drive
to new jack city for a younger man
with a better brain
I fell in love with you
no matter what you say
but you were right about the reasons
I don't want to be
what I'm becoming
your trophy wife
I know they wander
and find a young young man
you trophy wife
I know they wander
and find a young man
your trophy wife