TRAF1
TNF receptor-associated factor 1 is a protein that in humans is encoded by the TRAF1 gene.
Function
The protein encoded by this gene is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from various receptors of the TNFR superfamily. This protein and TRAF2 form a heterodimeric complex, which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF2 also interacts with inhibitor-of-apoptosis proteins (IAPs), and thus mediates the anti-apoptotic signals from TNF receptors. The expression of this protein can be induced by Epstein-Barr virus (EBV). EBV infection membrane protein 1 (LMP1) is found to interact with this and other TRAF proteins; this interaction is thought to link LMP1-mediated B lymphocyte transformation to the signal transduction from TNFR family receptors.
Interactions
TRAF1 has been shown to interact with:
Podcasts:
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by National
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by Suburban Legends
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by Insyderz
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by Alliswell
Trophy Wife
by: NationalNo nobody wants to be
no no one's lover
no matter what they say
lovers know they are the ones
who one day have to go
trophy wives
I know they wander
and find a young young man
trophy wives
I know they wander
one time you were a good rabbit
to all the girls
and all their lovely mothers
you tried a piece of everything
now nothing turns you on
trophy wives
I know they wander
and find a young young man
trophy wives
I know they wander
run run baby I don't feel alive
but I'm pretty and I'm pretty sure
I'm gonna be alright to drive
to new jack city for a younger man
with a better brain
I fell in love with you
no matter what you say
but you were right about the reasons
I don't want to be
what I'm becoming
your trophy wife
I know they wander
and find a young young man
you trophy wife
I know they wander
and find a young man
your trophy wife