TPD52L2

Tumor protein D54 is a protein that in humans is encoded by the TPD52L2 gene.

Model organisms

Model organisms have been used in the study of TPD52L2 function. A conditional knockout mouse line, called Tpd52l2^{tm1a(KOMP)Wtsi} was generated as part of the International Knockout Mouse Consortium program — a high-throughput mutagenesis project to generate and distribute animal models of disease to interested scientists.

Male and female animals underwent a standardized phenotypic screen to determine the effects of deletion.

Twenty two tests were carried out on mutant mice and one significant abnormality was observed: homozygous adult females displayed a decrease in body length by DEXA.

Interactions

TPD52L2 has been shown to interact with TPD52L1 and TPD52.

References

Further reading