Thyroid hormone receptor alpha (TR-alpha) also known as nuclear receptor subfamily 1, group A, member 1 (NR1A1), is a nuclear receptor protein that in humans is encoded by the THRA gene.
The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
THR1 has been shown to interact with:
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
Ooh Ooh
There's a storm, Thara
You should have seen the
Look upon you face
As I waved high
Had your hands moving all
Around the place
Up and down her thighs
Guess you weren't expecting me
See that was always out of my place
Now it's time for me to
Find another man
You say you want it, you need it
Although you had it, I'm leaving
Uh oh Uh oh Uh oh
Now your sitting there all by yourself
I don't need you, don't want you
Look in your eyes
And I see through uh oh uh oh
And you'll never see this ass again
Never thought that we
Would end like this
Or say goodbye
I know that you'll come back to me
Cause you miss my smile
Finally see, how you are treating me
So now your on your own
You say you want it, you need it
Although you had it, I'm leaving
Uh oh Uh oh Uh oh
Now your sitting there all by yourself
I don't need you, don't want you
Look in your eyes
And I see through uh oh uh oh
And you'll never see this ass again
[Rap:]
You say you want it, you need it
Although you had it, I'm leaving
Uh oh Uh oh Uh oh
Now your sitting there all by yourself
I don't need you, don't want you
Look in your eyes
And I see through uh oh uh oh
And you'll never see this ass again
Thara
Thara
Thara