Tetrahydrocannabivarin (THCV, THV) is a homologue of tetrahydrocannabinol (THC) having a propyl (3-carbon) side chain instead of a pentyl (5-carbon) group on the molecule, which makes it produce very different effects from THC. This terpeno-phenolic compound is found naturally in Cannabis, sometimes in significant amounts. The psychoactive effects of THCV in Cannabis preparations are not well characterized.
Similarly to THC, THCV has 7 double bond isomers and 30 stereoisomers (see: Tetrahydrocannabinol#Isomerism). Its melting point is < 220 degrees Celsius, < 428 degrees Fahrenheit.
Plants with elevated levels of propyl cannabinoids (including THCV) have been found in populations of Cannabis sativa L. ssp. indica (= Cannabis indica Lam.) from China, India, Nepal, Thailand, Afghanistan, and Pakistan, as well as southern and western Africa. THCV levels up to 53.7% of total cannabinoids have been reported.
THCV is a cannabinoid receptor type 1 antagonist and cannabinoid receptor type 2 partial agonist. Δ8-THCV has also been shown to be a CB1 antagonist. Both papers describing the antagonistic properties of THCV were demonstrated in murine models.
In a place where comfort shouldn't be
I found comfort and tranquility
I found friends that mean so much to me,
in a place I never thought I'd be.
the cave's never
coming down on me.
the cave really
means so much to me
'cause the cave, it only gives
I'm glad the cave is where I live
O.K., so sometimes things get out of hand
and piece of mind is in great demand
I climb up to the top...
look around and it all seems to stop
the cave's never coming down on me
and the cave really means so much to me
'cause the cave, it only gives
I'm glad the cave is where I live
the cave's never coming down on me
the cave really means so much to me
'cause the cave, it only gives