Thyroxine-binding globulin (TBG) is a globulin that binds thyroid hormones in circulation. It is one of three proteins (along with transthyretin and serum albumin) responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3’-triiodothyronine (T3) in the bloodstream. Of these three proteins, TBG has the highest affinity for T4 and T3 but is present in the lowest concentration. Despite its low concentration, TBG carries the majority of T4 in the blood plasma. Due to the very low concentration of T4 and T3 in the blood, TBG is rarely more than 25% saturated with its ligand. Unlike transthyretin and albumin, TBG has a single binding site for T4/T3. TBG is synthesized primarily in the liver as a 54-kDa protein. In terms of genomics, TBG is a serpin; however, it has no inhibitory function like many other members of this class of proteins.
TBG tests are sometimes used in finding the reason for elevated or diminished levels of thyroid hormone. This is done by measuring resin binding to labeled thyroid hormone, which happens only when the labeled thyroid hormone is free.
At night.. (yeahhh!)
At night.. (talkin bout - all that shit)
At night.. (better not go to sleep nigga)
At night.. (yeah! I see you nigga)
[Daz]
Smokin bomb, feelin loaded, forty yappin, smoke imported
Servin (?) fat as boulders, got a (?) on my shoulders
Homies robbin homies, on point with the po'-po's
Sellin white snow pure yo, twist a little bit just to get a lil' mo'
We had the ground, we bagged a round, crack, money in stripes
I lay you down, let niggaz know that we ain't no fuckin joke, niggahhh
[Kurupt]
The nighttime's, the right time, family and pride
Personally known for the way I, spray and ride
Silent if I, silent is the way I glide
Money'll make a nigga shift a pistol shoot to the sky
[Daz]
Nigga let's ride! I love it when the sun goes down
Nigga get chopped down, get gunned down
[Kurupt]
Run down, run around, and shot down
Popped down glocks in full pound surround
Get the homies together and call the shots, fallin on baller's blocks
Smaller and smaller knots, alcoholics lookin fo'
[D] my gangsta bitches (uh-huh) and busta niggaz (uh-huh)
[K] Liquor weed, pistols pills, niggaz shot and niggaz killed
At night.. (uh-huh, uh-huh, uh-huh)
At night.. (uh-huh)
(liquor weed, pistols pills, niggaz shot and niggaz killed)
At night.. (uh-huh, uh-huh)
At night.. (what ch'all niggaz wanna do, huh?)
[Kurupt]
I put holes in the air and turn black to blue
And I don't give a fuck about puttin holes in you
The midnight strike, the killer strikes the streets at night
Imitation Doggs on scope and it's on on sight (nigga)
[Daz]
Murder killin robbery, mayhem
Assault with the deadly weapons equals battery
I be down with the tragedy
Catch a nigga slippin, shoulda known
Nigga one-eighty-seven ain't shit but a misdemeanor
(If you ain't knowin - they ain't knowin)
Niggaz dyin unexpected, and they knowin
(They don't know) Niggaz tryin to make it echo
but it's showin (they ain't showin) little bitches on the street
straight hoein (straight hoein) you ain't knowin (thought you knew)
[Kurupt]
Overblown, got'n'gone, the song zone, at the zone shown
Time and time again it's on, Vietnam again
Napalm set-trip, coast-trip, post and get
tripped on, blastin fuckin chippin niggaz out the fuckin dash
What the fuck is this? Niggaz is the luckiest
Strike and spray, e'ryday all day around the way
I lost my homeboy last year, nigga shed his last tear
Comin through to blast shit, I knew I'd catch his ass crip
At night.. (uh-huh, uh-huh, uh-huh)
At night.. (uh-huh)
(liquor weed, pistols pills, niggaz shot and niggaz killed)
At night.. (uh-huh, uh-huh)
At night..
At night.. (yeahhh - that's how it go down e'ry night nigga)
At night.. (y'all niggaz better stay strapped)
(cause we on a hunt for all y'all)
At night.. (and we ain't takin no shorts)
(servin y'all niggaz on sight)
At night.. (everyday, all night, yeah)
At night.. (everyday, all day, anybody killer)
At night.. (fuck all y'all! yeah!)
At night..
Whassup whassup? Whatchu need?
(Got a fifty sack?) Whassup? Aww the police, c'mon!
{Police! Police! Up against the wall}