The Suzuki reaction is the organic reaction that is classified as a coupling reaction where the coupling partners are a boronic acid with a halidecatalyzed by a palladium(0) complex. It was first published in 1979 by Akira Suzuki and he shared the 2010 Nobel Prize in Chemistry with Richard F. Heck and Ei-ichi Negishi for their effort for discovery and development of palladium-catalyzed cross couplings in organic synthesis. In many publications this reaction also goes by the name Suzuki–Miyaura reaction and is also referred to as the "Suzuki Coupling". It is widely used to synthesize poly-olefins, styrenes, and substituted biphenyls. Several reviews have been published describing advancements and the development of the Suzuki Reaction. The general scheme for the Suzuki reaction is shown below where a carbon-carbon single bond is formed by coupling a organoboron species (R1-BY2) with a halide (R2-X) using a palladium catalyst and a base.
The new catalyst demonstrated extraordinary performance in Suzuki-Miyaura cross-coupling reactions—a Nobel Prize-winning technique used to form carbon-carbon (C‒C) bonds—essential in pharmaceuticals, agrochemicals and materials science.
