Ago

Ago or AGO may refer to:

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Argonaute

The Argonaute protein family plays a central role in RNA silencing processes, as essential catalytic components of the RNA-induced silencing complex (RISC). RISC complex is responsible for the gene silencing phenomenon known as RNA interference (RNAi). Argonaute proteins bind different classes of small non-coding RNAs, including microRNAs (miRNAs), small interfering RNAs (siRNAs) and Piwi-interacting RNAs (piRNAs). Small RNAs guide Argonaute proteins to their specific targets through sequence complementarity (base pairing), which then leads to mRNA cleavage or translation inhibition.

Discovery

The RNA interference (RNAi) was first reported in 1995 by Guo and Kemphues, and similar pathways collectively referred to as RNA silencing were discovered in plants and fungi. The beginning of people’s understanding of the mechanism of RNA silencing began only in 1998 with the experiments of Fire and colleagues demonstrating that double-stranded RNA triggered RNAi. RNA silencing pathways process long RNAs into small RNAs that direct the repression of transcription or translation of nucleic acid targets with sequence corresponding to the small RNAs. These single-stranded RNAs, referred to as guide strands, are incorporated into RNA silencing effectors complexes such as the RNA-induced silencing complex (RISC). These RNA silencing effector complexes contain Argonaute family proteins.

The Cataracs

The Cataracs was an American hip hop indie-pop production project (formerly duo) formed in Berkeley, California consisting of songwriter, vocalist, and producer Niles "Cyranizzy" Hollowell-Dhar (born 6 October 1988), and formerly songwriter and vocalist David "Campa" Benjamin Singer-Vine (born 1987). The duo started out as an independent group, during their years at Berkeley High School. The two were first signed to the label Indie-Pop. Singer-Vine left the group in August 2012 with Hollowell-Dhar continuing on with the name The Cataracs despite David's departure. Hollowell-Dhar also released materials starting 2014, under the name of KSHMR.

Biography

Early days

The duo met in their sophomore year while attending Berkeley High School. Singer-Vine was featured in a rap CD that was being passed around campus. When Dhar eventually heard the CD, he subsequently created a response. However, the “diss” response brought the two together and they soon became friends. In 2003, the two joined together to create what is now The Cataracs (named after the phrase “Who smoke ‘til your eyes get cataracts” from Snoop Dogg's song “What's my name Pt. 2”). In the summer of 2006, they released their first album, Technohop Vol. 1. In August 2006, the group joined with The Pack to make the single “Blueberry Afghani”. The song soon became a hit and was chosen as a “Download of the Week” by 106 KMEL and many music sites such as The Fader, UK’s Hip Hop Connection and XLR8R praised it.

Sunrise (Sacramento RT)

Sunrise is a side-platformed Sacramento RT light rail station in Rancho Cordova, California, United States. The station was opened on June 11, 2004, and is operated by the Sacramento Regional Transit District. As part of the Gold Line, it has service to Downtown Sacramento, California State University, Sacramento, Gold River and Folsom. The station is located on Folsom Boulevard just south of Highway 50 at the intersection of Sunrise Boulevard.

Sunrise, along with Zinfandel and Cordova Town Center, opened on June 11, 2004, as part of an $89 million, 2.8-mile (4.5 km) extension of the Gold Line east of the Mather Field/Mills station. Sunrise served as the eastern terminus for the Gold Line until the extension to Historic Folsom opened on October 15, 2005. Rancho Cordova city officials have stated the establishment of the stations will help in the development of transit-oriented development/redevelopment of the Folsom corridor through the city.

Sunrise serves as a major station on the eastern section of the Gold Line. Light rail operates from this stop to downtown at 15-minute intervals during peak time periods, while trains leave Folsom at 30-minute headways during this portion of the day. Many trains end their routes at this facility, as service between Folsom and Sunrise ceases as 7:30 p.m. every evening. Additionally, connection to RT Bus Route 74 can be made, and there is a 487-space park and ride lot located at the station.

Sunrise (1926 film)

Sunrise is a 1926 Australian silent film co-directed by Raymond Longford, who took over during filming. It was the second film from Australasian Films following their recommencement of production, after Painted Daughters.

It is considered a lost film.

Plot

George Willis loses his unfaithful wife in a rock fall and takes to the bush He rescues a girl, Hope Stuart, from a flood and nurses her back to health. When he brings her back to her father he discovers that an old enemy, Arthur Greerson, has accused him of murder.

Greerson is injured in a mining accident and after George rescues him, Greerson admits he has lied. George returns to his life as a recluse in the mountains, followed by Hope.

Cast

Production

The film was shot on location in the Blue Mountains at Bargo with interiors at the studios of Australasian Films in Bondi. F. Stuart Whyte began directing but left Australia during shooting for unknown reasons. He was replaced by Longford, who had recently contracted to Australasian Films.