WDM
WDM may refer to:
People
Indian locomotive class WDM-2
The class WDM-2 is Indian Railways' workhorse diesel locomotive. The first units were imported fully built from the American Locomotive Company (Alco) in 1962. Since 1964, it has been manufactured in India by the Diesel Locomotive Works (DLW), Varanasi. The model name stands for broad gauge (W), diesel (D), mixed traffic (M) engine. The WDM-2 is the most common diesel locomotive of Indian Railways.
The WDM-2A is a variant of the original WDM-2. These units have been retro-fitted with air brakes, in addition to the original vacuum brakes. The WDM-2B is a more recent locomotive, built with air brakes as original equipment. The WDM-2 locos have a maximum speed of 120 km/h (75 mph), restricted to 100 km/h (62 mph) when run long hood forward - the gear ratio is 65:18.
History
In the early 1960s Indian Railways began conversion of its mainline from steam to diesel locomotives. For this conversion General Motors Electro-Motive Division (EMD) and the American Locomotive Company (ALCO) were asked to submit designs for new diesel locomotives. Each company submitted prototypes. Indian Railways designated these prototypes the WDM-4 class and the WDM-2 class respectively. Technologically the General Motors WDM-4 was superior to ALCO's WDM-2, but Indian Railways required a transfer of technology agreement that would allow these locomotives to be manufactured in India. General Motors did not agree to the transfer of technology agreement so the ALCO prototype was selected for production. The first few prototype WDM-2s were imported. After Diesel Locomotive Works (DLW) completed construction of its factory in Varanasi, production of the locomotives began in India. The first 12 locos were built using kits imported from ALCO in the United States. After that DLW started manufacturing the WDM-2 locomotives from their own components. Since then over 2,800 locomotives have been manufactured and the WDM-2 has become the most popular locomotive in India.
STK
STK may refer to:
Tau-protein kinase
In enzymology, a tau-protein kinase (EC 2.7.11.26) is an enzyme that catalyzes the chemical reaction
Thus, the two substrates of this enzyme are ATP and tau protein, whereas its two products are ADP and O-phospho-tau-protein.
This enzyme belongs to the family of transferases, specifically those transferring a phosphate group to the sidechain oxygen atom of serine or threonine residues in proteins (protein-serine/threonine kinases). This enzyme participates in 14 metabolic pathways: erbb signaling pathway, cell cycle, wnt signaling pathway, hedgehog signaling pathway, axon guidance, focal adhesion, b cell receptor signaling pathway, insulin signaling pathway, melanogenesis, alzheimer's disease, colorectal cancer, endometrial cancer, prostate cancer, and basal cell carcinoma.
Nomenclature
The systematic name of this enzyme class is ATP:[tau-protein] O-phosphotransferase. Other names in common use include ATP:tau-protein O-hosphotransferase, brain protein kinase PK40erk, cdk5/p20, CDK5/p23, glycogen synthase kinase-3beta, GSK, protein tau kinase, STK31, tau kinase, [tau-protein] kinase, tau-protein kinase I, tau-protein kinase II, tau-tubulin kinase, TPK, TPK I, TPK II, and TTK.
Podcasts:
