Steviol is a diterpene first isolated from the plant Stevia rebaudiana in 1931. Its chemical structure was not fully elucidated until 1960.
Steviol occurs in the plant as steviol glycosides, sweet compounds that have found widespread use as sugar substitutes.
In Stevia rebaudiana, the biosynthesis of steviol is confined to green tissues. The precursors of steviol are synthesized via the non-mevalonate pathway located in plant cell plastids, which produces isopentenyl pyrophosphate (IPP) and dimethylallyl pyrophosphate (DMAPP). IPP and DMAPP are converted to geranylgeranyl diphosphate (GGDP), which is the precursor of many diterpenoids, by GGDP synthase. GPDP is made into a cyclic compound, copalyl diphosphate (CDP), by CDP synthase, after which kaurene is produced by another cyclization catalyzed by kaurene synthase.
The kaurene is then transferred to the endoplasmic reticulum, where it is oxidized to kaurenoic acid by kaurene oxidase in a reaction that uses up oxygen and NADPH. Then steviol is produced by hydroxylation. The steviol is subsequently glycosylated in the cytoplasm.
[verse: 1]
she said, "i need sometime to find myself,
i need a little space to think.
maybe we should start seeing other people.
baby, things are moving way to fast for me."
so, i, i picked up what was left of my pride,
and i put on my walking shoes,
and i got up on that high road,
and i did what any gentleman would do.
i, um...
[chorus]
i got a brand new girlfriend.
we went and jumped off the deep end,
flew out to LA for the weekend,
spent the whole day, lyin' on the beach,
wearin' nothin' but a smile,
playin' kissy-kissy, smoochy-smoochy,
talkin' mooshy-mooshy bout nothin'.
man, i think im on to somethin',
yano i feel just like a kid again.
i got a brand new girlfriend.
[verse: 2]
i love it when she calls me butter cup,
laughs and says i left the toilet seat up,
she pops and tosses me a cold beer,
and says my buddies always welcome here.
when i get hungry, she takes me out.
i ride the shotgun like a shitzu hound.
my tails a waggin', my tounges hangin' out,
it makes me wanna shout...
[chorus]
wooo...
cute, cute, cute...
she likes to write our names in the sand.
shes hearing wedding bells and making plans.
shes gonna hang around a while i guess.
she hasnt even told me she loves me yet.
[chorus]
she makes me feel just like a kid again,