Selective serotonin reuptake inhibitor
Selective serotonin re-uptake inhibitors or serotonin-specific reuptake inhibitors (SSRIs) are a class of drugs that are typically used as antidepressants in the treatment of major depressive disorder and anxiety disorders.
The exact mechanism of SSRIs is unknown. SSRIs are believed to increase the extracellular level of the neurotransmitter serotonin by limiting its reabsorption into the presynaptic cell, increasing the level of serotonin in the synaptic cleft available to bind to the postsynaptic receptor. They have varying degrees of selectivity for the other monoamine transporters, with pure SSRIs having only weak affinity for the norepinephrine and dopamine transporters.
SSRIs are the most widely prescribed antidepressants in many countries. The efficacy of SSRIs in mild or moderate cases of depression has been disputed.
Medical uses
The main indication for SSRIs is major depressive disorder (also called "major depression", "clinical depression" and often simply "depression"). SSRIs are frequently prescribed for anxiety disorders, such as social anxiety disorder, panic disorders, obsessive–compulsive disorder (OCD), eating disorders, chronic pain and occasionally, for posttraumatic stress disorder (PTSD). They are also frequently used to treat depersonalization disorder, although generally with poor results.
SSRI (disambiguation)
SSRI is an acronym that stands for several things, including:
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Dreaming
by: Zero 7I?ve sworn, my love
I?ve been reborn, my love
Don?t be forlorn, my love
I?ve torn my heart
Do not mourn my depart
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There's nothing they can do
Now, I'm reborn, my love
Yeah, you must believe
You?ll live on without me
I?m leaving all my love
I am awake and you are only dreaming
You?ll be okay and you will find some meaning
You will not break, though, you'll buckle with feelings
I am awake and you are only dreaming
Don?t fear my friend 'cause there is no real end
I?ve been reborn, my love
I?m happy here, I have nothing to fear
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So, shed a tear for all the happy years
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We?ll need all our love
I am awake and you are only dreaming
You?ll be okay and you will find some meaning
You will not break, though, you'll buckle with feelings
I am awake and you are only dreaming
I am awake and you are only dreaming
You?ll be okay and you will find some meaning
You will not break, though, you'll buckle with feelings
Latest News for: ssri
Cognitive deficits in depression often persist after SSRI treatment, research shows
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