Spina bifida

Spina bifida (Latin: "split spine") is a birth defect where there is incomplete closing of the backbone and membranes around the spinal cord. There are three main types: spina bifida occulta, meningocele, and myelomeningocele. The most common location is the lower back, but in rare cases it may be the middle back or neck. Occulta has no or only mild signs. Signs of occulta may include a hairy patch, dimple, dark spot, or swelling on the back at the site of the gap in the spine. Meningocele typically causes mild problems with a sac of fluid present at the gap in the spine. Myelomeningocele, also known as open spina bifida, is the most severe form. Associated problems include poor ability to walk, problems with bladder or bowel control, hydrocephalus, a tethered spinal cord, and latex allergy. Learning problems are relatively uncommon.

Spina bifida is believed to be due to a combination of genetic and environmental factors. After having one child with the condition or if one of the parents has the condition, there is a 4% chance that the next child will also be affected. Not having enough folate in the diet during pregnancy also plays a significant role. Other risk factors include certain antiseizure medications, obesity, and poorly controlled diabetes. Diagnosis may occur either before or after a child is born. Before birth if a blood test or amniocentesis finds a high level of alpha-fetoprotein (AFP), there is a higher risk of spina bifida. Ultrasound examination may also detect the problem. Medical imaging can confirm the diagnosis after birth. It is a type of neural tube defect with other types including anencephaly and encephalocele.

Spina

Spina was an Etruscan port city, established by the end of the 6th century BCE, on the Adriatic at the ancient mouth of the Po, south of the lagoon which would become the site of Venice. The site of Spina was lost until modern times, when drainage schemes in the delta of the Po River in 1922 first officially revealed a necropolis of Etruscan Spina about four miles west of the commune of Comacchio. The fishermen of Comacchio, it soon turned out, had been the source of "Etruscan" vases (actually originally imported from Greece) and other artifacts that had appeared for years on the archeological black market. The archaeological finds from the burials of Spina were discovered with the help of aerial photography. Aside from the white reflective surfaces of the modern drainage channels there appeared in the photographs a ghostly network of dark lines and light rectangles, the former indicating richer vegetation on the sites of ancient canals. Thus the layout of the ancient trading port was revealed, now miles from the sea, due to the sedimentation of the Po delta. Spina may have had a Hellenised indigenous population.

Circus (building)

The Roman circus (from Latin, "circle") was a large open-air venue used for public events in the ancient Roman Empire. The circuses were similar to the ancient Greek hippodromes, although circuses served varying purposes and differed in design and construction. Along with theatres and amphitheatres, Circuses were one of the main entertainment sites of the time. Circuses were venues for chariot races, horse races, and performances that commemorated important events of the empire were performed there. For events that involved re-enactments of naval battles, the circus was flooded with water.

According to Edward Gibbon, in Chapter XXXI of his work The History of the Decline and Fall of the Roman Empire, the Roman people, at the start of the 5th century:

Architectural design

The performance space of the Roman circus was normally, despite its name, an oblong rectangle of two linear sections of race track, separated by a median strip running along the length of about two thirds the track, joined at one end with a semicircular section and at the other end with an undivided section of track closed (in most cases) by a distinctive starting gate known as the carceres, thereby creating a circuit for the races. The Circus of Maxentius epitomises the design.