Plač

Plač (pronounced [ˈplaːtʃ]) is a settlement in the Municipality of Kungota in the western part of the Slovene Hills (Slovene: Slovenske gorice) in northeastern Slovenia.

The parish church in the village is dedicated to Saint Andrew and belongs to the Roman Catholic Archdiocese of Maribor. The church was first mentioned in written documents dating to 1197. The current building dates to between 1652 and 1657 with some details of the Gothic building still visible. The belfry dates to the 19th century.

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PLA

PLA may refer to:

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Phospholipase A2

Phospholipases A2 (PLA2s) EC 3.1.1.4 are enzymes that release fatty acids from the second carbon group of glycerol. This particular phospholipase specifically recognizes the sn-2 acyl bond of phospholipids and catalytically hydrolyzes the bond releasing arachidonic acid and lysophospholipids. Upon downstream modification by cyclooxygenases, arachidonic acid is modified into active compounds called eicosanoids. Eicosanoids include prostaglandins and leukotrienes, which are categorized as anti-inflammatory and inflammatory mediators.

PLA2 enzymes are commonly found in mammalian tissues as well as arachnid, insect and snake venom. Venom from both snakes and insects is largely composed of melittin, which is a stimulant of PLA2. Due to the increased presence and activity of PLA2 resulting from a snake or insect bite, arachidonic acid is released from the phospholipid membrane disproportionately. As a result, inflammation and pain occur at the site. There are also prokaryotic A2 phospholipases.