| Solute carrier family 6 (amino acid transporter), member 14 | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||||||
| Symbols | SLC6A14; BMIQ11 | ||||||||||||
| External IDs | OMIM: 300444 MGI: 1890216 HomoloGene: 38290 GeneCards: SLC6A14 Gene | ||||||||||||
|
|||||||||||||
| RNA expression pattern | |||||||||||||
 |
|||||||||||||
| More reference expression data | |||||||||||||
| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 11254 | 56774 | |||||||||||
| Ensembl | ENSG00000087916 | ENSMUSG00000031089 | |||||||||||
| UniProt | Q9UN76 | Q9JMA9 | |||||||||||
| RefSeq (mRNA) | NM_007231.3 | NM_020049.4 | |||||||||||
| RefSeq (protein) | NP_009162.1 | NP_064433.3 | |||||||||||
| Location (UCSC) | Chr X: 115.57 – 115.59 Mb |
Chr X: 21.29 – 21.32 Mb |
|||||||||||
| PubMed search | [1] | [2] | |||||||||||
Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+) is a protein that in humans is encoded by the SLC6A14 gene.[1][2]
SLC6A14 is a member of the Na(+)- and Cl(-)-dependent neurotransmitter transporter family and transports both neutral and cationic amino acids in an Na(+)- and Cl(-)-dependent manner.[supplied by OMIM][2]
References [link]
- ^ Sloan JL, Mager S (Sep 1999). "Cloning and functional expression of a human Na(+) and Cl(-)-dependent neutral and cationic amino acid transporter B(0+)". J Biol Chem 274 (34): 23740–5. DOI:10.1074/jbc.274.34.23740. PMID 10446133.
- ^ a b "Entrez Gene: SLC6A14 solute carrier family 6 (amino acid transporter), member 14". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=11254.
Further reading [link]
- Ohman M, Oksanen L, Kaprio J, et al. (2000). "Genome-wide scan of obesity in Finnish sibpairs reveals linkage to chromosome Xq24.". J. Clin. Endocrinol. Metab. 85 (9): 3183–90. DOI:10.1210/jc.85.9.3183. PMID 10999806.
- Sloan JL, Grubb BR, Mager S (2003). "Expression of the amino acid transporter ATB 0+ in lung: possible role in luminal protein removal.". Am. J. Physiol. Lung Cell Mol. Physiol. 284 (1): L39–49. DOI:10.1152/ajplung.00164.2002 (inactive 2008-10-03). PMID 12388375.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. DOI:10.1073/pnas.242603899. PMC 139241. PMID 12477932. //www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241.
- Suviolahti E, Oksanen LJ, Ohman M, et al. (2004). "The SLC6A14 gene shows evidence of association with obesity". J. Clin. Invest. 112 (11): 1762–72. DOI:10.1172/JCI200317491. PMC 281637. PMID 14660752. //www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=281637.
- Durand E, Boutin P, Meyre D, et al. (2004). "Polymorphisms in the amino acid transporter solute carrier family 6 (neurotransmitter transporter) member 14 gene contribute to polygenic obesity in French Caucasians". Diabetes 53 (9): 2483–6. DOI:10.2337/diabetes.53.9.2483. PMID 15331564.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. DOI:10.1101/gr.2596504. PMC 528928. PMID 15489334. //www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=528928.
- Ross MT, Grafham DV, Coffey AJ, et al. (2005). "The DNA sequence of the human X chromosome". Nature 434 (7031): 325–37. DOI:10.1038/nature03440. PMC 2665286. PMID 15772651. //www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2665286.
- Gupta N, Miyauchi S, Martindale RG, et al. (2005). "Upregulation of the amino acid transporter ATB0,+ (SLC6A14) in colorectal cancer and metastasis in humans". Biochim. Biophys. Acta 1741 (1–2): 215–23. DOI:10.1016/j.bbadis.2005.04.002. PMID 15905073.
 |
This article on a gene on the X chromosome and/or its associated protein is a stub. You can help Wikipedia by expanding it. |
https://wn.com/SLC6A14
Podcasts:
PLAYLIST TIME: