Pentagonal prism

In geometry, the pentagonal prism is a prism with a pentagonal base. It is a type of heptahedron with 7 faces, 15 edges, and 10 vertices.

As a semiregular (or uniform) polyhedron

If faces are all regular, the pentagonal prism is a semiregular polyhedron, more generally, a uniform polyhedron, and the third in an infinite set of prisms formed by square sides and two regular polygon caps. It can be seen as a truncated pentagonal hosohedron, represented by Schläfli symbol t{2,5}. Alternately it can be seen as the Cartesian product of a regular pentagon and a line segment, and represented by the product {5}x{}. The dual of a pentagonal prism is a pentagonal bipyramid.

The symmetry group of a right pentagonal prism is D_5h of order 20. The rotation group is D₅ of order 10.

Volume

The volume, as for all prisms, is the product of the area of the pentagonal base times the height or distance along any edge perpendicular to the base. For a uniform pentagonal prism with edges h the formula is

Pip (counting)

Pips are small but easily countable items. The term is used to describe the dots on dominoes and dice, the symbols that denote suits and value of playing cards, as the name for the small seeds of some fruit, and sometimes as a synonym for "dot" in morse code.

Dice

On dice, pips are small dots on each face of a common six-sided die. These pips are typically arranged in patterns denoting the numbers one through six. The sum of opposing faces traditionally adds up to seven. Pips are commonly colored black on white dice, and white on dice of other colors, although colored pips on white dice are not uncommon; Asian dice often have an enlarged red single pip for the "one" face, while the dice for the game Kismet feature black pips for 1 and 6, red pips for 2 and 5, and green pips for 3 and 4.

Dominoes

Dominoes use pips that are similar to dice. Each half of a domino tile can have anywhere from no pips to six pips arranged in the same manner to dice pips. Some sets designed for more than four players may have more than six pips.

Phosphatidylinositol 4,5-bisphosphate

Phosphatidylinositol 4,5-bisphosphate or PtdIns(4,5)P₂, also known simply as PIP₂, is a minor phospholipid component of cell membranes. PtdIns(4,5)P₂ is enriched at the plasma membrane where it is a substrate for a number of important signaling proteins.

PtdIns(4,5)P₂ is formed primarily by the type I phosphatidylinositol 4-phosphate 5-kinases from PI(4)P. In metazoans, PtdIns(4,5)P₂ can also be formed by type II phosphatidylinositol 5-phosphate 4-kinases from PI(5)P.

The fatty acids of PtdIns(4,5)P₂ are variable in different species and tissues, but studies show the most common fatty acids are stearic in position 1 and arachidonic in 2.

Functions

IP₃/DAG pathway

PtdIns(4,5)P₂ functions as an intermediate in the [IP₃/DAG pathway], which is initiated by ligands binding to G protein-coupled receptors activating the G_q alpha subunit. PtdIns(4,5)P₂ is a substrate for hydrolysis by phospholipase C (PLC), a membrane-bound enzyme activated through protein receptors such as α1 adrenergic receptors. PtdIns(4,5)P₂ regulates the function of many membrane proteins and ion channels, such as the M-channel. The products of the PLC catalyzation of PtdIns(4,5)P₂ are inositol 1,4,5-trisphosphate (InsP₃; IP₃) and diacylglycerol (DAG), both of which function as second messengers. In this cascade, DAG remains on the cell membrane and activates the signal cascade by activating protein kinase C (PKC). PKC in turn activates other cytosolic proteins by phosphorylating them. The effect of PKC could be reversed by phosphatases. IP₃ enters the cytoplasm and activates IP₃ receptors on the smooth endoplasmic reticulum (ER), which opens calcium channels on the smooth ER, allowing mobilization of calcium ions through specific Ca²⁺ channels into the cytosol. Calcium participates in the cascade by activating other proteins.

Siren

Siren or sirens may refer to:

Most common uses

Animals

Places

Music

Artists

Albums

Siren

Sirens

Kevin Coyne

Kevin Coyne (27 January 1944 – 2 December 2004) was a musician, singer, composer, film-maker, and a writer of lyrics, stories and poems. The former "anti-star" was born on 27 January 1944 in Derby, UK, and died in his adopted home of Nuremberg, Germany, on 2 December 2004.

Coyne is notable for his unorthodox style of blues-influenced guitar composition, the intense quality of his vocal delivery, and his bold treatment of injustice to the mentally ill in his lyrics. Many influential musicians have described themselves as Coyne fans, among them Sting and John Lydon. In the mid-1970s, prior to the formation of The Police, Coyne's band included guitarist Andy Summers. Prominent BBC disc jockey and world music authority Andy Kershaw has described Coyne as "a national treasure who keeps getting better" and as one of the great British blues voices.

Over many years Coyne produced the distinctive art work for many of his own album covers but his move to Germany, in the 1980s, saw his work on full-size paintings blossom in its own right.

Siren (video game)

Siren (サイレン, Sairen), known as Forbidden Siren in the PAL regions, is a survival horror video game developed by Project Siren, a development team of SCE Japan Studio, for the PlayStation 2 in 2003. The story revolves around an interconnected cast of characters that possess a power which enables them to see and hear what a nearby character sees. The game was followed by a PlayStation 2 sequel, a reimagining for the PlayStation 3 and a film adaption.

Gameplay

Siren is divided into stages, each taking place in one of ten areas in the village of Hanuda, and organized chronologically in a table called the "Link Navigator". In order to complete a stage, the player must accomplish a primary objective that usually involves reaching an exit point, subduing undead enemies called "Shibito", or finding an item. Objectives in different stages are interconnected via a butterfly effect, and a character's actions in one stage can trigger a secondary objective in another stage.

There are miscellaneous items scattered throughout each stage that give the player further insight into the plot's background. Once obtained, these items are archived in a catalog and can be viewed at any time during the game's duration. The game's player characters possess a psychic power named "sightjack," which enables them to see and hear what a nearby Shibito or human sees and hears, and thus pinpoint its position, as well as gain knowledge of their activities and of the position of obtainable items. The clarity of each target depends on the distance from the player character. Once a point of view is located, it can be assigned to one of certain buttons of the controller to easily switch between multiple points of view. However, the player character is unable to move during use of the ability and is thus vulnerable to attack.