"Music" is a 2001 hit single by Erick Sermon featuring archived vocals from Marvin Gaye.
The song was thought of by Sermon after buying a copy of Gaye's Midnight Love and the Sexual Healing Sessions album, which overlook some of the original album's earlier mixes. After listening to an outtake of Gaye's 1982 album track, "Turn On Some Music" (titled "I've Got My Music" in its initial version), Sermon decided to mix the vocals (done in a cappella) and add it into his own song. The result was similar to Natalie Cole's interpolation of her father, jazz great Nat "King" Cole's hit, "Unforgettable" revisioned as a duet. The hip hop and soul duet featuring the two veteran performers was released as the leading song of the soundtrack to the Martin Lawrence & Danny DeVito comedy, "What's the Worst That Could Happen?" The song became a runaway success rising to #2 on Billboard's R&B chart and was #1 on the rap charts. It also registered at #21 pop giving Sermon his highest-charted single on the pop charts as a solo artist and giving Gaye his first posthumous hit in 10 years following 1991's R&B-charted single, "My Last Chance" also bringing Gaye his 41st top 40 pop hit. There is also a version that's played on Adult R&B stations that removes Erick Sermon's rap verses. The song was featured in the 2011 Matthew McConaughey film The Lincoln Lawyer.
Music is the fourth album and first album on J Records by hip hop artist Erick Sermon. It was received well critically and commercially. Its success was fueled by its title track "Music" which sampled vocals from Marvin Gaye and in terms of chart position is Sermon's most popular song, peaking at #22, along with inclusion on the soundtrack of the Martin Lawrence/Danny DeVito film What's the Worst That Could Happen?; the music video for the song featured scenes from the film intermixed with clips of Gaye performing in archived music videos and music programs. "Music" propelled the album to reach #33 on The Billboard 200 chart making it Sermon's second most popular solo album.
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Music (foaled 1810) was a British Thoroughbred racehorse and broodmare who won the classic Oaks Stakes at Epsom Downs Racecourse in 1813. Music's success in the Guineas was the only win in a seven race career and gave her owner George FitzRoy, 4th Duke of Grafton the first of twenty classic wins. Music was sold and exported to Ireland at the end of her three-year-old season.
Music was a bay mare bred by Augustus FitzRoy, 3rd Duke of Grafton at his stud at Euston Hall in Suffolk. On the third Duke's death in 1811 ownership of the stud and the yearling filly passed to his son George FitzRoy, 4th Duke of Grafton. Her dam, Woodbine was a half-sister to the good broodmare Hornby Lass and herself produced several other winners including the 1815 Oaks winner Minuet. Music was sired by the 1790 Epsom Derby winner Waxy, who became an influential and important stallion, siring two additional Oaks winners and four winners of the Derby. Grafton sent the filly to be trained at Newmarket by Robert Robson, the so-called "Emperor of Trainers".
Sigma Seven Co., Ltd. (株式会社シグマ・セブン, Kabushiki-gaisha Shiguma Sebun) is a Japanese talent management firm representing a fair number of voice actors and entertainers. Founded on March 3, 1988, Sigma Seven is headquartered on the third floor of the Haga Building in Minato, Tokyo, Japan.
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The SDS Sigma series was a series of computers that was introduced by Scientific Data Systems in 1966. The first machines in the series were the 16-bit Sigma 2 and the 32-bit Sigma 7; the Sigma 7 was the first 32-bit computer released by SDS. At the time the only competition for the Sigma 7 was the IBM 360.
Memory size increments for all SDS/XDS/Xerox computers was stated in kWords, not kBytes. For example, the Sigma 5 base memory was 16K 32-Bit words (64K Bytes). Maximum memory was limited by the length of the instruction address field of 17 bits, or 128K Words (512K Bytes). Although this is a trivial amount of memory in today's technology, Sigma systems performed their tasks exceptionally well, and few were deployed with, or needed, the maximum 128K Word memory size.
The Xerox 500 series computers, introduced starting in 1973, were compatible upgrades to the Sigma systems using newer technology.
In 1975 Xerox sold its computer business to Honeywell, Inc. which continued support for the Sigma line for a time.
The sigma-1 receptor (σ1R), one of two sigma receptor subtypes, is a chaperone protein at the endoplasmic reticulum (ER) that modulates calcium signaling through the IP3 receptor. In humans, the σ1 receptor is encoded by the SIGMAR1 gene.
The σ1 receptor is a transmembrane protein expressed in many different tissue types. It is particularly concentrated in certain regions of the central nervous system. It has been implicated in myriad phenomena, including cardiovascular function, schizophrenia, clinical depression, the effects of cocaine abuse, and cancer. Much is known about the binding affinity of hundreds of synthetic compounds to the σ1 receptor.
An endogenous ligand for the σ1 receptor has yet to be conclusively identified, but tryptaminergic trace amines, as well as neuroactive steroids such as dehydroepiandrosterone (DHEA) and pregnenolone all activate the receptor.
The σ1 receptor is defined by its unique pharmacological profile. In 1976 Martin reported that the effects of N-allylnormetazocine (SKF-10,047) could not be due to activity at the μ and κ receptors (named from the first letter of their selective ligands morphine and ketazocine, respectively) and a new type of opioid receptor was proposed; σ (from the first letter of SKF-10,047). However, ligands acting at this new “opioid” receptor were not blocked by the classical opioid antagonists naloxone and naltrexone. Consequently, the opioid classification was eventually dropped and the receptor was later termed the σ1 receptor. It was found to have affinity for the (+)-stereoisomers of several benzomorphans (e.g., (+)-pentazocine and (+)-cyclazocine), various structurally and pharmacologically distinct psychoactive chemicals such as haloperidol and cocaine, and neuroactive steroids like progesterone.
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Caleb Joshua Shomo (born December 1, 1992 Age 23) is the lead vocalist of hardcore band Beartooth, the former lead vocalist of metalcore band Attack Attack!, and the owner of Studio Records in Columbus, Ohio. Shomo joined Attack Attack! as keyboardist at 15 years old while maintaining a passion for electronic music and eventually grew into record production by 18.
Attack Attack! was an American Metalcore band from Westerville, Ohio, formed in 2005 with Caleb Shomo as the keyboardist in 2008, synth player and programmer when he was 15, of which his influences contributed to the bands electronic sounds, and started doing lead clean and unclean vocals on October 19, 2009 when former vocalist Nick Barham left the group. Shomo features clean vocals on tracks 1 to 5 and 17 and 18 of their deluxe release of self titled Attack Attack! In 2008 they signed to Rise Records and released their debut album Someday Came Suddenly on November 11. It peaked on the Billboard 200 at number 193.