SIB-1553A is a nicotinic acetylcholine receptor agonist that is selective for receptors with a β4 subunit. Administration of SIB-1553A improved memory and attention in a Parkinson's disease model.
SIB or sib may refer to:
Sib is a technical term in the discipline of anthropology which originally denoted a kinship group among Anglo-Saxon and other Germanic peoples. In an extended sense, it then became the standard term for a variety of other kinds of lineal (matrilineal or patrilineal) or cognatic (i.e.,descended through links of both sexes) kinship groups. The word may also denote a member of such a group.
American anthropologists often used the term 'sib' as the generic term for a category that breaks down into the sub-classifications of patri-sib, referring to patrilineal clan descent, and matri-sib, to refer to matrilineal clan descent.
SIB-1757 is a drug used in scientific research which was one of the first compounds developed that acts as a selective antagonist for the metabotropic glutamate receptor subtype mGluR5. It has anti-hyperalgesia effects in animals. SIB-1757 along with other mGluR5 antagonists has been shown to have neuroprotective and hepatoprotective effects, and it is also used to study the role of the mGluR5 receptor in brain development.