Shox

Shox: Rally Reinvented is an arcade-style rally game developed by EA Sports Big. It is available on the PlayStation 2 console in Europe, USA and Japan.

Gameplay

Shox: Rally Reinvented (Shox) features three environments where all tracks are based upon: Arid (a desert-like, sandy environment), Jungle (a jungle-themed, muddy environment), and Ice (an arctic, snowy and icy environment). In every track there are three "Shoxzones", areas the player must cross while being timed. When the player reaches the end of a Shoxzone, the player is rewarded with cash based on the time taken to cross it, divided into Gold, Silver and Bronze. However, if the player takes too long to cross the zone, beyond the Bronze time, a reward will not be given.

Shox also features the concept of a "Shoxwave", a sort of shockwave that follows the track ahead of the player's car if they successfully pass, within Gold time, through all three Shoxzones, and is activated on the next 'checkpoint' (for lack of a better word) (it is not required to achieve Gold time in each Shoxzone within a single lap). During the duration of its presence, the player will be continually earning cash, but the Shoxzone system will be temporarily disabled. The objective of the Shoxwave, should it be activated, is to drive fast enough to catch up to it before it reaches the next checkpoint. While approaching the Shoxwave, the screen will appear increasingly blurry and distorted and make driving at high speed more difficult. Should the player fail to catch up in time, the Shoxwave will disappear and the Shoxzone system will resume. On the other hand, if the player succeeds, the Shoxwave will speed ahead of the player upon passing the checkpoint, for the player to catch up to again.

Short stature homeobox gene

The short stature homeobox (SHOX) gene is a gene, located on both the X and Y chromosomes, which is associated with short stature in humans if mutated or present in only one copy (haploinsufficiency).

Pathology

The gene was first found during a search for the cause of short stature in women with Turner syndrome, in which there is loss of genetic material from the X chromosome, classically by loss of one entire X chromosome.

Since its discovery, the SHOX gene has been found to play a role in idiopathic short stature (short stature of unknown cause without other symptoms), Léri-Weill dyschondrosteosis, and Langer mesomelic dysplasia.

Gene dosage effects of extra copies of SHOX may be a cause of the increased stature seen in other sex chromosome aneuploidy conditions such as 47,XXX, 47,XYY, 47,XXY, 48,XXYY, etc.

Function

The SHOX gene is a homeobox gene, meaning that it helps regulate development. The SHOX gene is composed of 6 different exons and is located in the pseudoautosomal region (PAR1) of the X chromosome and Y chromosome. Experiments have found similar genes in a variety of animals and insects.

SHOX2

Short stature homeobox 2, also known as homeobox protein Og12X or paired-related homeobox protein SHOT, is a protein that in humans is encoded by the SHOX2 gene.

Function

SHOX2 is a member of the homeobox family of genes that encode proteins containing a 60-amino acid residue motif that represents a DNA-binding domain. Homeobox proteins have been characterized extensively as transcriptional regulators involved in pattern formation in both invertebrate and vertebrate species.

Clinical significance

Several human genetic disorders are caused by aberrations in human homeobox genes. This locus represents a pseudoautosomal homeobox gene that is thought to be responsible for idiopathic short stature, and it is implicated in the short stature phenotype of Turner syndrome patients. This gene is considered to be a candidate gene for Cornelia de Lange Syndrome.

SHOX2 localises on chromosome 3, so it is an autosomal and not a pseudoautosomal homeobox (SHOX, which localises on the PAR1 region of chromosome X and Y, has a pseudoautosomal hereditability).

Shanti

Shanti, Santhi or Shanthi (from Sanskrit शान्तिः śāntiḥ; √ शम śam: ‘be calm’) means peace, rest, calmness, tranquility, or bliss.

The poet T. S. Eliot, in his poem The Waste Land (where he spelled it Shantih) translated it as "The Peace which passeth understanding"

In Sanskrit

People

Music

Shanti (film)

Shanti (Kannada: ಶಾಂತಿ, English: Peace) is a film in the Kannada language directed by renowned Kannada writer and director Baraguru Ramachandrappa. The film features only a single actor and hence has found an entry in the Guinness World Records in the category Fewest actors in a narrative film.Bhavana (Not to be confused with the Malayalam actress of the same name) is the only actress in this film and there are no other actors.

Theme

Baraguru Ramachandrappa decided to direct this film to portray different faces of peace by juxtaposing symbolism and monologues. The main theme of the film is to explore the various ways to fight terrorism without any compromise with the human values promoted by the United Nations. The UN was used as a vital aspect in the film since Baragur feels that it is a world body that has created two contradicting influences of war and peace. Baragur indicates that though this was sort of an experiment, experimentation was not the main motivation for producing this film. Rather than the concept, more focus has been given on the creative aspects of the theme. A female character was chosen as the sole actress in the film since peace is generally considered feminine whereas war is more masculine. The film does not end with a moral, something uncommon among Indian movies. This is because Baraguru wanted the audience to start off a discussion to weigh the pros and cons of war against peace.

Shanti (TV series)

Shanti - Ek Aurat Ki Kahani is an Indian television series that aired on DD National in 1994, and was later shown on Indian television channel STAR Plus. The series stars Mandira Bedi as Shanti in the main lead. The show is one of the first Indian television drama series, has received a considerable cult status and is considered a classic.

Synopsis

The story begins with two friends of the biggest Bollywood production house in the country. Two friends - Kamesh Mahadevan and Raj G.J. Singh writer, directors and producers live in the lavish Shanti Mansion. Behind the walls of Shanti Mansion lie dark secrets of the past lives of both the friends.

Plot

Every character has a past and has something hidden, it all gets revealed when Shanti, an aspiring journalist hoping to write the biographies of Kamesh and Raj, arrives. The duo they only approve of a movie when it is appreciated by the servants of the house and tell of how they went from rags to riches.

Then are shown the family members, Kamesh's eldest son Ramesh is mentally challenged. Younger son Somesh is a failing director struggling over the script which gets rejected even by his own father. His wife Ayesha is the daughter of a film producer whose career was ruined by the duo. His adopted daughter Nidhi was revealed to be the illegitimate daughter of Kamesh. Raj's wife took to Ashrams and Sadhus, while his youngest son Nihal returns with an American white friend Michelle, who accidentally revealed that she is his wife. His elder daughter Maya is drawn to depression by her mother's absence, while his womanizer elder son Rohan is forced to marry a model Sasha after she threatens to come out to the press.