Shivering (also called shuddering) is a bodily function in response to early hypothermia or just feeling cold in warm-blooded animals. When the core body temperature drops, the shivering reflex is triggered to maintain homeostasis. Skeletal muscles begin to shake in small movements, creating warmth by expending energy. Shivering can also be a response to a fever, as a person may feel cold. During fever the hypothalamic set point for temperature is raised. The increased set point causes the body temperature to rise (pyrexia), but also makes the patient feel cold until the new set point is reached. Severe chills with violent shivering are called rigors. Rigors occur because the patient's body is shivering in a physiological attempt to increase body temperature to the new set point.
Located in the posterior hypothalamus near the wall of the third ventricle is an area called the primary motor center for shivering. This area is normally inhibited by signals from the heat center in the anterior hypothalamic-preoptic area but is excited by cold signals from the skin and spinal cord. Therefore, this center becomes activated when the body temperature falls even a fraction of a degree below a critical temperature level.
Shiver is the first studio album by the country music artist Jamie O'Neal. Released on October 31, 2000, the album reached its peak of number 14 on the U.S. Top Country Albums chart and number 125 on the Billboard 200. It was certified Gold by the RIAA for sales of 500,000. The album was released through Mercury Nashville Records. Five singles were released from Shiver, the first two ("There Is No Arizona" and "When I Think About Angels") managed to reach number 1 on the Billboard Hot Country Songs chart.
The album included a duet with the country singer Mark Wills, who also recorded for Mercury at the time. The track, "I'm Not Gonna Do Anything Without You", was released as a single for Wills, and reached number 31 on the country charts. The song is also available on Wills' studio album, Loving Every Minute.
After the release of this album, O'Neal recorded a second album for Mercury, entitled On My Way to You. Although its lead-off single peaked at number 34 in 2003, the album was not released and O'Neal exited Mercury. She then signed to Capitol Records Nashville to release her next album, Brave (2005).
Maggie Stiefvater (STEE-vah-tǝr; born November 18, 1981) is an American writer of Young Adult fiction. She currently lives in Virginia.
Stiefvater was born Heidi Hummel in Harrisonburg, Virginia. After being home-schooled from sixth grade on, Maggie Stiefvater attended Mary Washington College, graduating with a B.A. in history. After graduating, she worked as a portrait artist, specializing in equestrian art, which is collected internationally. At 16, she legally changed her first name from Heidi to Margaret. She is married and has two children.
Stiefvater published her first novel, Lament, in 2008. Before Lament had been released, she sold the rights to Ballad, the sequel to Lament, and to Shiver, the first book in The Wolves of Mercy Falls trilogy.Shiver spent more than 40 weeks on the New York Times Bestseller List. In 2010, Linger debuted at the number one spot on the New York Times Bestseller List. There are over 1.7 million copies of The Wolves of Mercy Falls series in print and more than thirty-six foreign editions have been licensed.
In physics and thermodynamics, an equation of state is a relation between state variables. More specifically, an equation of state is a thermodynamic equation describing the state of matter under a given set of physical conditions. It is a constitutive equation which provides a mathematical relationship between two or more state functions associated with the matter, such as its temperature, pressure, volume, or internal energy. Equations of state are useful in describing the properties of fluids, mixtures of fluids, solids, and even the interior of stars.
The most prominent use of an equation of state is to correlate densities of gases and liquids to temperatures and pressures. One of the simplest equations of state for this purpose is the ideal gas law, which is roughly accurate for weakly polar gases at low pressures and moderate temperatures. However, this equation becomes increasingly inaccurate at higher pressures and lower temperatures, and fails to predict condensation from a gas to a liquid. Therefore, a number of more accurate equations of state have been developed for gases and liquids. At present, there is no single equation of state that accurately predicts the properties of all substances under all conditions.
PVT is an experimental rock band based in London and Sydney and are currently signed to Brooklyn imprint Felte and have released records on Warp Records in the past. Band members are Richard Pike, Laurence Pike and Dave Miller. Brothers Richard and Laurence grew up in Sydney, later meeting Dave Miller who originally comes from Perth, Australia. The band have released four albums, three EPs and a number of singles. They have toured internationally.
In 1999, PVT was formed as Pivot in Sydney by brothers Richard Pike and Laurence Pike. The band spent the subsequent four years developing their sound and working on their debut album, with guitarist Richard Pike producing. They released their debut album, Make Me Love You, in August 2005 on Sensory Records. It was nominated for a J Award by national youth broadcaster Triple J. The band added Perth (and now London) electronica artist Dave Miller in late 2005, omitting the old members from their line up and becoming a three piece.
Pvt1 oncogene (non-protein coding), also known as PVT1, is a long non-coding RNA gene. In mice, this gene was identified as a breakpoint site in chromosome 6;15 translocations. These translocations are associated with murine plasmacytomas. The equivalent translocation in humans is t(2;8), which is associated with a rare variant of Burkitt's lymphoma. In rats, this breakpoint was shown to be a common site of proviral integration in retrovirally induced T lymphomas.Transcription of PVT1 is regulated by Myc.