Security-Enhanced Linux (SELinux) is a Linux kernel security module that provides a mechanism for supporting access control security policies, including United States Department of Defense–style mandatory access controls (MAC).
SELinux is a set of kernel modifications and user-space tools that have been added to various Linux distributions. Its architecture strives to separate enforcement of security decisions from the security policy itself and streamlines the volume of software charged with security policy enforcement. The key concepts underlying SELinux can be traced to several earlier projects by the United States National Security Agency.
From NSA Security-enhanced Linux Team:
A Linux kernel integrating SELinux enforces mandatory access-control policies that confine user programs and system servers access to files and network resources. Limiting privilege to the minimum required to work reduces or eliminates the ability of these programs and daemons to cause harm if faulty or compromised (via buffer overflows or misconfigurations, for example). This confinement mechanism operates independently of the traditional Linux (discretionary) access control mechanisms. It has no concept of a "root" super-user, and does not share the well-known shortcomings of the traditional Linux security mechanisms (such as a dependence on setuid/setgid binaries).