Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase

Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase (EC 3.1.3.86, SHIP1, SHIP2, SHIP, p150Ship) is an enzyme with system name 1-phosphatidyl-1D-myo-inositol-3,4,5-trisphosphate 5-phosphohydrolase. This enzyme catalyses the following chemical reaction

This enzyme hydroylses 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) to produce PtdIns(3,4)P2.

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SEA

SEA or Sea may refer to:

Organizations

Science and technology

90.9 Sea FM

90.9 Sea FM (callsign 4SEA) is a radio station on the Gold Coast, Queensland, Australia. It is part of the Southern Cross Austereo Today Network, and is also the network hub for the regional Today Stream, broadcasting shows at times from 9am - 12am across the Sea, Star and Hot FM Networks across Australia.

The Sea FM brand name and original logo was created by Gold Coast Broadcasters Pty Ltd for just the one station - 90.9 Sea FM - after the Gold Coast was granted a new commercial FM licence. 90.9 Sea FM began broadcasting in 1989 with programming consulted by Austereo. The original Sea FM on-air line-up was a strong team of experienced Announcers, many having made their name previously in Metropolitan radio including - Craig Bruce (FOX FM) & Sammy Power, Ian 'Lofty' Fulton (4IP), Grahame "Durry" Rodgers (2SM & 2NX), Sue Moses (2MMM & Channel 10), Gregg Easton (2UW & 4BK), Joe Miller (3XY & EON FM), Dean Miller and Simon Franks.

In November 2011, controversy erupted after rumours surfaced that popular long-term breakfast co-host, Moyra Major, was to be replaced by entertainer Charli Robinson, after Robinson had filled in for six weeks while Major was on maternity leave. It was reported that Major had been replaced due to a significant increase in ratings for the breakfast show during Robinson's stint as co-host.

Collins-class submarine replacement project

Identified as the most expensive defence procurement project to date in Australian history, the Collins-class replacement will provide Australia with a submarine capability deep into the twenty-first century. With the Royal Australian Navy's (RAN's) Collins-class submarines scheduled to begin leaving service from 2025 onwards, plans to replace them began in 2007 with the commencement of the defence acquisition project SEA 1000, also referred to as the Future Submarine Programme. Australia's unique operating environment (including significant variations in ocean climate and conditions) and rejection of nuclear propulsion had previously driven it to operate in the Collins-class the world's largest diesel-electric submarines, capable of transiting the long distances from HMAS Stirling to their deployment areas.

In the early phases of the replacement project, four design options were identified: purchase a Military-Off-The-Shelf (MOTS) design, modify a MOTS design for Australian conditions, design an evolution of the Collins-class, or create a new design. Nuclear propulsion has been ruled out due to the lack of an indigenous nuclear industry in Australia and public opposition to nuclear technology.

Bird

Birds (class Aves) are a group of endothermic vertebrates, characterised by feathers, a beak with no teeth, the laying of hard-shelled eggs, a high metabolic rate, a four-chambered heart, and a lightweight but strong skeleton. Birds live worldwide and range in size from the 5 cm (2 in) bee hummingbird to the 2.75 m (9 ft) ostrich. They rank as the class of tetrapods with the most living species, at approximately ten thousand, with more than half of these being passerines, sometimes known as perching birds or, less accurately, as songbirds.

The fossil record indicates that birds are the last surviving dinosaurs, having evolved from feathered ancestors within the theropod group of saurischian dinosaurs. True birds first appeared during the Cretaceous period, around 100 million years ago, and the last common ancestor is estimated to have lived about 95 million years ago. DNA-based evidence finds that birds radiated extensively around the time of the Cretaceous–Paleogene extinction event that killed off the non-avian dinosaurs. Birds in South America survived this event and then migrated to other parts of the world via multiple land bridges while diversifying during periods of global cooling. Primitive bird-like "stem-birds" that lie outside class Aves proper, in the group Avialae, have been found dating back to the mid-Jurassic period. Many of these early stem-birds, such as Archaeopteryx, were not yet capable of fully powered flight, and many retained primitive characteristics like toothy jaws in place of beaks and long bony tails.

The finger

In Western culture, the finger or the middle finger (as in giving someone the (middle) finger or the bird or flipping someone off,) is an obscene hand gesture. It communicates moderate to extreme contempt, and is roughly equivalent in meaning to "fuck off", "fuck you", "shove it up your ass", "up yours" or "go fuck yourself". It is performed by showing the back of a closed fist that has only the middle finger extended upwards, though in some locales the thumb is extended. Extending the finger is considered a symbol of contempt in several cultures, especially Western ones. Many cultures use similar gestures to display their disrespect, although others use it to express pointing without intentional disrespect toward other cultures.

The gesture dates back to Ancient Greece and it was also used in Ancient Rome. Historically, it represented the phallus. In some modern cultures, it has gained increasing recognition as a sign of disrespect, and has been used by music artists (notably more common among hardcore punk bands and rappers), actors, celebrities, athletes, and politicians. Most still view the gesture as obscene. The index finger and ring finger besides the middle finger in more contemporary periods has been likened to represent the testicles.

Birds (Marius Neset album)

Birds (released March 25, 2013 in Oslo, Norway by the label Edition Records – EDN1040) is the 4'th album of the Norwegian saxophonist Marius Neset.

Critical reception

The review by Neil Spencer of the British newspaper The Guardian awarded the album 5 stars, the review by Terje Mosnes of the Norwegian newspaper Dagbladet awarded the album dice 6, the review by Carl Petter Opsahk of the Norwegian newspaper Verdens Gang awarded the album dice 5, and the reviewer Ian Mann of the Jazz Mann awarded the album 4.5 stars

According to Mosnes, with this album, Neset takes further steps on his way to the Jazz sky. The brilliant compositions and the musical skills of this band are extraordinary. It is only to look forward to the next move of this great jazz musician and composer.

NRK Jazz critique Erling Wicklund, in his review of Neset's album Birds states:

BBC Music critique Peter Marsh, in his review of Neset's album Birds states:

Track listing

Personnel