Coordinates: 53°46′05″N 2°37′16″W / 53.768°N 2.621°W / 53.768; -2.621
Samlesbury /ˈsɑːmzbᵊri/ is a village and civil parish in the borough of South Ribble in Lancashire, England. Samlesbury Hall, a historic house, is located in the village as is Samlesbury Aerodrome. The village is also home to a large modern brewery owned by Anheuser-Busch InBev. The population of the Civil Parish taken at the 2011 census was 1,206.
The village's name is derived from the Old English sceamol, meaning ledge and burh meaning fortification, hence literally "ledge fortification". It may also be that the name at least partly derives from the Roman name for the River Ribble and its eponymous Celtic deity, Belisama.
In the 13th and 14th centuries there was fortified house near the river, probably a stone tower, held ny the Denyas family. It was destroyed by the Scots in one of their raids, possibly the Great Raid of 1322. A family heiress, Alicia Denyas, married Gilbert de Southworth, builder of Samlesbury Hall.