Saccharopine is an intermediate in the metabolism of amino acid lysine. It is a precursor of lysine in the alpha-aminoadipate pathway which occurs in a few lower fungi, the higher fungi, and euglenids. In mammals and higher plants saccharopine is an intermediate in the degradation of lysine, formed by condensation of lysine and alpha-ketoglutarate.
The reactions involved, catalysed by saccharopine dehydrogenases, are:
Saccharopinuria (high amounts of saccharopine in the urine) and saccharopinemia (an excess of saccharopine in the blood) are conditions present in some inherited disorders of lysine degradation.
Saccharopine was first isolated in 1961 from yeasts (Saccharomyces, hence the name) by Darling and Larsen.
Just woke up
but it's not a dream
you're still and I'm freaking
don't wanna know 'bout your plans
don't know how this shit began
psycho
You say you love me
I bite my lip
But inside I am screaming
This is it I'm about to flip
You're staying But I wish you were leaving
You're P-S-Y-C-H-O
I thought that you ought to know
why can't you just let me be
You're turning psycho on me
You better rethink your life
I'll never be your wife
I feel just like deadly
You're turning psycho on me
Whoa baby
no baby
don't wanna know baby
leave baby
me baby
You're turining psycho on me
You call my house
you ask my friends
you wanna know how I'm doing
Real cute stuff but I call the bluff
You bitter you don't think I know it
So whip the tears out of your eyes
The guilt trip thing isn't working
get your tounge out of my mouth
It's more then just a little disturbing
You're P-S-Y-C-H-O
I thought that you ought to know
why can't you just let me be
You're turning psycho on me
You better rethink your life
I'll never be your wife
I feel just like deadly
You're turning psycho on me
Whoa baby
no baby
don't wanna know baby
leave baby
me baby
You're turining psycho on me
psycho
crazy
psycho
psycho
You're P-S-Y-C-H-O
I thought that you ought to know
why can't you just let me be
You're turning psycho on me
You better rethink your life
I'll never be your wife
I feel just like deadly
You're turning psycho on me
Whoa baby
no baby
don't wanna know baby
leave baby
me baby
You're turining psycho on me
you better rethink your life
Don't come back here no more
knocking on my door
I don't want you around
Leave me alone
Whoa baby
no baby
don't wanna know baby
leave baby
me baby